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Calr4 Gene Detail
Summary
  • Symbol
    Calr4
  • Name
    calreticulin 4
  • Synonyms
    4933403L16Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2140435
    NCBI Gene: 108802
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr4:109091682-109111768 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 51.10 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    169 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2140435
 protein coding gene Chr4:109075610-109112176 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028568
 protein coding gene Chr4:109992094-110030349 (+)
A/J MGP_AJ_G0028531
 protein coding gene Chr4:106031137-106067105 (+)
AKR/J MGP_AKRJ_G0028478
 protein coding gene Chr4:108672303-108707967 (+)
BALB/cJ MGP_BALBcJ_G0028550
 protein coding gene Chr4:106245817-106281787 (+)
C3H/HeJ MGP_C3HHeJ_G0028264
 protein coding gene Chr4:109414575-109454821 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028990
 protein coding gene Chr4:113941864-113977979 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026281
 protein coding gene Chr4:101343631-101364042 (+)
CAST/EiJ MGP_CASTEiJ_G0027700
 protein coding gene Chr4:107266441-107303980 (+)
CBA/J MGP_CBAJ_G0028233
 protein coding gene Chr4:117689139-117733501 (+)
DBA/2J MGP_DBA2J_G0028381
 protein coding gene Chr4:105651476-105687740 (+)
FVB/NJ MGP_FVBNJ_G0028349
 protein coding gene Chr4:104528755-104564285 (+)
LP/J MGP_LPJ_G0028482
 protein coding gene Chr4:110233607-110272018 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028375
 protein coding gene Chr4:122877721-122914808 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029026
 protein coding gene Chr4:108911191-108950682 (+)
PWK/PhJ MGP_PWKPhJ_G0027426
 protein coding gene Chr4:103939890-103976443 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027250
 protein coding gene Chr4:106293487-106329646 (+)
WSB/EiJ MGP_WSBEiJ_G0027781
 protein coding gene Chr4:109090358-109126251 (+)



Homology
more
  • Human Ortholog
    CALR4P, calreticulin 4, pseudogene
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CALR4P, calreticulin 4, pseudogene
  • Links
    NCBI Gene ID: 441884

  • Chr Location
    1p32.3; chr1:51561866-51594897 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    13
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000028558 Ensembl Gene Model | MGI Sequence Detail 20087 C57BL/6J ±  kb
transcript ENSMUST00000030285 Ensembl | MGI Sequence Detail 1606 Not Applicable  
polypeptide ENSMUSP00000030285 Ensembl | MGI Sequence Detail 420 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR009169 Calreticulin
    IPR001580 Calreticulin/calnexin
    IPR018124 Calreticulin/calnexin, conserved site
    IPR009033 Calreticulin/calnexin, P domain superfamily
    IPR013320 Concanavalin A-like lectin/glucanase domain superfamily
Molecular
Reagents
less
  • All nucleic 13
    cDNA 13

    Microarray probesets 3
Other
Accession IDs
less
MGI:1918281
References
more
  • Summaries
    All 32
    Developmental Gene Expression 2
    Gene Ontology 1
    Phenotypes 10
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:313609 Diaz Del Moral S, et al., Deletion of the Wilms' Tumor Suppressor Gene in the Cardiac Troponin-T Lineage Reveals Novel Functions of WT1 in Heart Development. Front Cell Dev Biol. 2021;9:683861
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
05/21/2024
MGI 6.23 		The Jackson Laboratory