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Tmed5 Gene Detail
Summary
  • Symbol
    Tmed5
  • Name
    transmembrane p24 trafficking protein 5
  • Synonyms
    3110020O18Rik, 4432412D15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921586
    NCBI Gene: 73130
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:108269422-108280486 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 5, 52.49 cM, cytoband E5
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    122 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921586
protein coding gene Chr5:108254232-108280486 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029850
protein coding gene Chr5:110173616-110200654 (-)
A/J MGP_AJ_G0029814
protein coding gene Chr5:105954792-105981086 (-)
AKR/J MGP_AKRJ_G0029759
protein coding gene Chr5:109365256-109395138 (-)
BALB/cJ MGP_BALBcJ_G0029826
protein coding gene Chr5:107091068-107116941 (-)
C3H/HeJ MGP_C3HHeJ_G0029548
protein coding gene Chr5:109836083-109867831 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030280
protein coding gene Chr5:114678075-114707903 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027514
protein coding gene Chr5:101013886-101029202 (-)
CAST/EiJ MGP_CASTEiJ_G0028962
protein coding gene Chr5:108755468-108781678 (-)
CBA/J MGP_CBAJ_G0029516
protein coding gene Chr5:118554838-118584479 (-)
DBA/2J MGP_DBA2J_G0029662
protein coding gene Chr5:106083027-106109370 (-)
FVB/NJ MGP_FVBNJ_G0029619
protein coding gene Chr5:104811213-104837367 (-)
LP/J MGP_LPJ_G0029750
protein coding gene Chr5:110768477-110797137 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029651
protein coding gene Chr5:123447185-123474015 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030314
protein coding gene Chr5:108935712-108962116 (-)
PWK/PhJ MGP_PWKPhJ_G0028675
protein coding gene Chr5:104898514-104925650 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028513
protein coding gene Chr5:106453829-106483276 (-)
WSB/EiJ MGP_WSBEiJ_G0029035
protein coding gene Chr5:109234588-109268277 (-)



Homology
more
  • Human Ortholog
    TMED5, transmembrane p24 trafficking protein 5
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMED5, transmembrane p24 trafficking protein 5
  • Synonyms
    CGI-100, p24g2, p28
  • Links
    NCBI Gene ID: 50999
    neXtProt AC: NX_Q9Y3A6
    UniProt: Q9Y3A6

  • Chr Location
    1p22.1; chr1:93149742-93180516 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 73130 NCBI Gene Model | MGI Sequence Detail 11065 C57BL/6J ±  kb
transcript NM_028876 RefSeq | MGI Sequence Detail 3871 C57BL/6  
polypeptide Q9CXE7 UniProt | EBI | MGI Sequence Detail 229 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 115
    cDNA 115

    Microarray probesets 7
Other
Accession IDs
less
MGI:1920380
References
more
  • Summaries
    All 33
    Gene Ontology 4
    Phenotypes 9
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory