Fig1C. from [doi:10.1016/S1074-7613(00)80609-3] Immunity 9(2): 267-76, Varfolomeev EE; Schuchmann M; Luria V; Chiannilkulchai N; Beckmann JS; Mett IL; Rebrikov D; Brodianski VM; Kemper OC; Kollet O; Lapidot T; Soffer D; Sobe T; Avraham KB; Goncharov T; Holtmann H; Lonai P; Wallach D, Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally. Copyright 1998 [PMID:9729047]