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Shh sonic hedgehog ( MGI:98297)
TS15 (9.5 dpc)
in situ hybridisation

Data Images
Figure 7A, Dufort et al., 1998 [PMID:9671576] . Copyright: This image is from Development and is displayed with the permission of the Company of Biologists Ltd. who owns the copyright.

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Expression Pattern Description
Spatial Annotation:
EMAGE:47Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
(what is wlz format?)
Download all expression domains: EMAGE:47_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
neural tube floor plate
detected detected
detected detected
regionalexpressed in gut endoderm
detected detected
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Entity Detected:Shh, sonic hedgehog ( MGI:98297)
Notes:Probe used used in this study by Dufort et al., 1998 [PMID:9671576] is referenced as being used by Echelard et al., 1993 [PMID:7916661] . Echelard et al. describe two Shh probes.
Age:9.5 dpc
Theiler Stage:TS15
Mutations:none (wild-type)
Staining procedure:undefined
General Information
Authors:Dufort et al., 1998 [PMID:9671576] Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:9671576] Dufort D, Schwartz L, Harpal K, Rossant J 1998 The transcription factor HNF3beta is required in visceral endoderm for normal primitive streak morphogenesis. Development (125):3015-25
 [ doi:10.1016/0092-8674(93)90627-3] [ PMID:7916661] Echelard Y, Epstein DJ, St-Jacques B, Shen L, Mohler J, McMahon JA, McMahon AP 1993 Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity. Cell (75):1417-30
Links:MGI:1289471 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI