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EMAGE:1003

Fgf15 fibroblast growth factor 15 ( MGI:1096383)
TS14 (16 Somite no.)
in situ hybridisation

Data Images
EMAGE:1003 EMAGE:1003
Figure 7F of Ishibashi & McMahon, 2002 [PMID:12361972] . Copyright: This image is from Development and is displayed with permission of The Company of Biologists Ltd. who owns the copyright. Figure 7D of Ishibashi & McMahon, 2002 [PMID:12361972] . Copyright: This image is from Development and is displayed with permission of The Company of Biologists Ltd. who owns the copyright.

Expression pattern clarity: two stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image annotations: Arrowheads indicate diencephalon-midbrain boundary. Arrows indicate midbrain-hindbrain isthmus. Both of these embryos are TS14 but only the data from the embryo shown in Fig 7D has been spatially mapped in this EMAGE entry.
Expression Pattern Description
Spatial Annotation:
EMAGE:1003Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
1003_wholemount_strong_3D_1.wlz
1003_wholemount_moderate_3D_1.wlz
1003_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:1003_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
future diencephalon
detected detected
regionalCompared to earlier stages, there is a ventral to dorsal expansion in diencephalic and midbrain primordia. Expression extended dorsally, overlapping Dbx1 and Tcf4 domains; also strongly expressed just posterior to the midbrain-hindbrain isthmus
future hindbrain
detected detected
regionalCompared to earlier stages, there is a ventral to dorsal expansion in diencephalic and midbrain primordia. Expression extended dorsally, overlapping Dbx1 and Tcf4 domains; also strongly expressed just posterior to the midbrain-hindbrain isthmus
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:2676494
Entity Detected:Fgf15, fibroblast growth factor 15 ( MGI:1096383)
Notes:The probe used in this study by Ishibashi & McMahon, 2002 [PMID:12361972] is of undefined sequence.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:16 Somite no.
Theiler Stage:TS14
Mutations:none (wild-type)
Preparation:wholemount
Procedures
Fixation:4% paraformaldehyde
General Information
Authors:Ishibashi & McMahon, 2002 [PMID:12361972] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:12361972] Ishibashi M, McMahon AP 2002 A sonic hedgehog-dependent signaling relay regulates growth of diencephalic and mesencephalic primordia in the early mouse embryo. Development (129):4807-19
Links:MGI:2676619 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI