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EMAGE:1010

Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 ( MGI:1353450)
TS16 (9.5 dpc)
in situ hybridisation

Data Images
EMAGE:1010
Fig 2A Mic et al, 2002 [PMID:11959834] . Copyright: This image is from Development and is displayed with the permission of the Company of Biologists Ltd who owns the copyright.

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image annotation: dr - dorsal retina.
Expression Pattern Description
Spatial Annotation:
EMAGE:1010Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
1010_wholemount_strong_3D_1.wlz
1010_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:1010_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
optic cup
detected detected
regionalExpression is in the dorsal retina
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:2180336
Entity Detected:Aldh1a1, aldehyde dehydrogenase family 1, subfamily A1 ( MGI:1353450)
Notes:The Aldh1a1 (Raldh1) probe used in this study by Mic et al, 2002 [PMID:11959834] is described as that used by Hsu et al., 1999 [PMID:10191271] . Hsu et al do not describe any in situ hybridisation probes but do describe a probe used for Northern hybridisation which was "the 3�-untranslated region".
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Strain:129S1/Sv x 129X1/SvJ x C57BL/6
Age:9.5 dpc
Theiler Stage:TS16
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Mic et al, 2002 [PMID:11959834] Indexed by GXD, Spatially mapped by EMAGE
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1042/0264-6021:3390387] [ PMID:10191271] Hsu LC, Chang WC, Hoffmann I, Duester G 1999 Molecular analysis of two closely related mouse aldehyde dehydrogenase genes: identification of a role for Aldh1, but not Aldh-pb, in the biosynthesis of retinoic acid. Biochem J (339):387-95
 [ PMID:11959834] Mic FA, Haselbeck RJ, Cuenca AE, Duester G 2002 Novel retinoic acid generating activities in the neural tube and heart identified by conditional rescue of Raldh2 null mutant mice. Development (129):2271-82
Links:MGI:2180871 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI