EMAGE mouse gene expression spatial database

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EMAGE:1013

Ascl1 achaete-scute complex homolog 1 (Drosophila) ( MGI:96919)
TS20 (12.5 dpc)
in situ hybridisation

Data Images


Figure 5F of Corbin et al., 2003 [PMID:12930780] . Copyright: This image is from Development and is displayed with permission of The Company of Biologists Ltd. who owns the copyright.

Expression pattern clarity:
Find spatially similar expression patterns:

Notes:

Image annotation: Arrow shows the dorsal limit of Ascl1 gene expression.

Expression Pattern Description

Spatial Annotation:

Annotation colour key:

	strong
	moderate
	weak
	possible
	not detected

3D mapping

3D context movie

View mapped 3D expression image

Download individual expression domains:

1013_voxel_strong_3D_1.wlz

1013_voxel_notDetected_3D_1.wlz

(what is wlz format?)

Download all expression domains:

EMAGE:1013_all_domains.zip

Find spatially similar expression patterns:

Morphological match to the template:

Text Annotation:

Structure

Level

Pattern

Notes

telencephalon

detected

regional

Annotation Validation:

EMAGE Editor

Detection Reagent

Type:	in situ hybridisation probe
Identifier:	MGI:23138
Entity Detected:	Ascl1, achaete-scute complex homolog 1 (Drosophila) ( MGI:96919)
Sequence:	sense strand is shown >MGI:23138 CAACAGCCGCAGGCGCCGCCGCAGCAGGCGCCGCAGCTGAGCCCGGTGGCCGACAGCCAGCCCTCAGGGG GCGGTCACAAGTCAGCGGCCAAGCAGGTCAAGCGCCAGCGCTCGTCCTCTCCGGAACTGATGCGCTGCAA ACGCCGGCTCAACTTCAGCGGCTTCGGCTACAGCCTGCCACAGCAGCAGCCGGCCGCCGTGGCGCGCCGC AACGAGCGCGAGCGCAACCGGGTCAAGTTGGTCAACCTGGGTTTTGCCACCCTCCGGGAGCATGTCCCCA ACGGCGCGGCCAACAAGAAGATGAGCAAGGTGGAGACGCTGCGCTCGGCGGTCGAGTACATCCGCGCGCT GCAGCAGCTGCTGGACGAGCACGACGCGGTGAGCGCTGCCTTTCAGGCGGGCGTCCTGTCGCCCACCATC TCCCCCAACTACTCCAACGACTTGAACTCTATGGCGGGTTCTCCGGTCTCGTCCTACTCCTCCGACGAGG GATCCTACGACCCTCTTAGCCCAGAGGAACAAGAGCTGCTGGACTTTACCAACTGGTTCTGAGGACCTGC CAGGCTCTCCTGGGAATGGACTTTGGAAGCAGGATGGCAGCAGATCCTGCATCTTTAGTGTTTCTCGCCA ACGACGTCAAATGGGGAGGCAGAAAAACAAGGGGAAAAAAGAAGAAGAAATGAAACAAACAAACCAGACA GCCAACCTACAGGGGCACCTTCACTAGATGCAATGTTCTCAGCAAACAGGGGTGGGCTCCAACAGTGTCT CTGCATTCCAACATCATTTCCAGACACGAGAAGAGTGACTGGTGTCTGAACCTAAGCCCGAATCACAGAT GGGTTCCTTTCCTGGAGCAAGAGCGTCACACACACACACACACACACAGACAGACACTATATTAACTCCC AACCACTAACAGGCAGGGCTGGAAGCGCGCATGTGCAAGTGCCTTCACCTCCCACTCTCTGTCAGAGCTG TCTTAGCCCCCTGAAACTGGGTTGATGTCTTTCCTCAGTCACCCCCATTCCAGCGATCTATGGACATTTG CC
	nt 239 - nt 1290 of NM_008553.2
Notes:	The Acsl1 (Mash1) probe used in this study by Corbin et al., 2003 [PMID:12930780] is described as that used by Guillemot & Joyner 1993 [PMID:8217843] ie "Clone 2", which is "1.1kb long, started at position aa48 of Mash-1 coding sequence and ended 0.5kb dowmstream of the stop codon in the 3' untranslated region".
Chemistry:	RNA
Strand:	antisense
Label:	digoxigenin

Specimen

Organism:	mouse
Age:	12.5 dpc
Theiler Stage:	TS20
Mutations:	none (wild-type)
Preparation:	section

Procedures

Fixation:	4% paraformaldehyde
Embedding:	cryosection

General Information

Authors:	Corbin et al., 2003 [PMID:12930780] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:	EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:	non-screen
References:	[ doi:10.1242/dev.00717] [ PMID:12930780] Corbin JG, Rutlin M, Gaiano N, Fishell G 2003 Combinatorial function of the homeodomain proteins Nkx2.1 and Gsh2 in ventral telencephalic patterning. Development (130):4895-906
	[ doi:10.1016/0925-4773(93)90006-J] [ PMID:8217843] Guillemot F, Joyner AL 1993 Dynamic expression of the murine Achaete-Scute homologue Mash-1 in the developing nervous system. Mech Dev (42):171-85
Links:	MGI:2676243 same experiment
	Ensembl same gene
	Allen Brain Atlas same gene
	BioGPS same gene
	International Mouse Knockout Project Status same gene
	GEISHA Chicken ISH Database same gene
	EMBL-EBI Gene Expression Atlas same gene
	BrainStars same gene
	ViBrism same gene
Data Source