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EMAGE:1047

Bmp4 bone morphogenetic protein 4 ( MGI:88180)
TS16 (10.5 dpc)
in situ hybridisation

Data Images
EMAGE:1047
Figure 5J of Furuta et al., 1997 [PMID:9187146] . Copyright: This image is from Development and is displayed with permission of The Company of Biologists Ltd. who owns the copyright.

Expression pattern clarity: two stars
Find spatially similar expression patterns: Find spatially similar patterns
Expression Pattern Description
Spatial Annotation:
EMAGE:1047EMAGE:1047Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
3D mapping3D context movie

View mapped 3D expression image EMAGE genex expression entry
Download individual expression domains:
1047_voxel_strong_3D_1.wlz
1047_voxel_moderate_3D_1.wlz
1047_voxel_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:1047_all_domains.zip
Find spatially similar expression patterns: EMAGE spatially similar patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
future brain
detected detected
regionalExpression pattern is similar to Hfh4 [Foxj1].
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:18808
Entity Detected:Bmp4, bone morphogenetic protein 4 ( MGI:88180)
Notes:The probe used in this study by Furuta et al., 1997 [PMID:9187146] was originally described in Jones et al., 1991 [PMID:1893873] ie. as "approx 1kb from the 5' region" that was made by "eliminating the 3' portion of the (1.6kb) cDNA, encoding the conserved TGFbeta region, by digestion with SmaI, and subsequent religation". This eliminated region spans nt 1035-1749 of X56848.1. Personal communication from B.Hogan: This clone "contains 5' non-coding and 5' coding regions up to before the conserved region (does not contain the mature region)"
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Strain:ICR
Age:10.5 dpc
Theiler Stage:TS16
Mutations:none (wild-type)
Preparation:section
Procedures
General Information
Authors:Furuta et al., 1997 [PMID:9187146] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:9187146] Furuta Y, Piston DW, Hogan BL 1997 Bone morphogenetic proteins (BMPs) as regulators of dorsal forebrain development. Development (124):2203-12
 [ PMID:1893873] Jones CM, Lyons KM, Hogan BL 1991 Involvement of Bone Morphogenetic Protein-4 (BMP-4) and Vgr-1 in morphogenesis and neurogenesis in the mouse. Development (111):531-42
Links:MGI:1276853 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI