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EMAGE:1064

T brachyury ( MGI:98472)
TS14 (8.5 dpc)
in situ hybridisation

Data Images
EMAGE:1064
Figure 9 (left) of van den Akker et al., 2002 [PMID:11959827] Copyright: This image is from Development and is displayed with the permission of The Company of Biologists Ltd. who owns the copyright.

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Expression Pattern Description
Spatial Annotation:
EMAGE:1064Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
1064_wholemount_strong_3D_1.wlz
1064_wholemount_moderate_3D_1.wlz
1064_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:1064_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
unsegmented mesenchyme
detected detected
regionalThe expression extends anteriorly to a position located one somite posterior to the last formed somite.
head somite
not detected not detected
homogeneous
trunk somite
not detected not detected
homogeneous
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:2449091
Entity Detected:T, brachyury ( MGI:98472)
Sequence:sense strand is shown

>MGI:2449091
CCTGGAATTCGTCCACCCCCTGTCCTACTTTAGTGAGACACAAGGTACACCTCTAATGTCCTCCCTTGTT
GCCTTAGAGTAGTTAACTTTGAGGACAGAAAAAAGCATAGCCAGAAGATTGTAACTGAACCGTCAACTGT
TCTGCCCTTGGAACATGCCTACTTTAAGCACACGTAGCTTTTTGTGTTGGGAAGTCAACTGTATGGATAC
TTTTCTGTTGACAAAGTAGCCAAAGACAATCTGCAGAAAGTGTTTTCTGCATAATAAAGGCAATATATAG
CACCTGG
nt 1760 - nt 2046 of X51683.1
Notes:The T probe used in this study by van den Akker et al., 2002 [PMID:11959827] is indicated as that described by Wilkinson et al., 1990 [PMID:1689462] ie: "from residue 1,760 to the end residue in the 3'-untranslated region of T-gene RNA (Herrmann et al., 1990 [PMID:2154694] )".
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Age:8.5 dpc
Theiler Stage:TS14
Mutations:Cdx1tm1Pgr/Cdx1+
Preparation:wholemount
Procedures
General Information
Authors:van den Akker et al., 2002 [PMID:11959827] Indexed by GXD, Spatially Mapped by EMAGE
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:11959827] van den Akker E, Forlani S, Chawengsaksophak K, de Graaff W, Beck F, Meyer BI, Deschamps J 2002 Cdx1 and Cdx2 have overlapping functions in anteroposterior patterning and posterior axis elongation. Development (129):2181-93
 [ doi:10.1038/343657a0] [ PMID:1689462] Wilkinson DG, Bhatt S, Herrmann BG 1990 Expression pattern of the mouse T gene and its role in mesoderm formation. Nature (343):657-9
 [ doi:10.1038/343617a0] [ PMID:2154694] Herrmann BG, Labeit S, Poustka A, King TR, Lehrach H 1990 Cloning of the T gene required in mesoderm formation in the mouse. Nature (343):617-22
Links:MGI:2180356 same experiment
 MGI:2154514 allele description
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE