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EMAGE:1261

Six3 sine oculis-related homeobox 3 homolog (Drosophila) ( MGI:102764)
TS12 (8.5 dpc)
in situ hybridisation

Data Images
EMAGE:1261
Figure 6Bc of Kurokawa et al., 2004 [PMID:15201223] Copyright: This image is from Development and is displayed with the permission of The Company of Biologists Ltd. who owns the copyright.

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Expression Pattern Description
Spatial Annotation:
EMAGE:1261Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
1261_wholemount_strong_3D_1.wlz
1261_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:1261_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
future brain
detected detected
regionalExpression is in anterior neurectoderm
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:1315062
Entity Detected:Six3, sine oculis-related homeobox 3 homolog (Drosophila) ( MGI:102764)
Notes:Probe used in this study by Kurokawa et al., 2004 [PMID:15201223] is indicated as being described by Oliver et al., 1995 [PMID:8575305] . Oliver et al., 1995 describe a number of "Bluescript KS II+ subclones containing different coding regions of Six3" as in situ hybridisation probes.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:8.5 dpc
Theiler Stage:TS12
Mutations:none (wild-type)
Preparation:wholemount
Procedures
Fixation:Bouin's fixation
Staining procedure:alkaline phosphatase + unspecified
General Information
Authors:Kurokawa et al., 2004 [PMID:15201223] Indexed by GXD, Spatially Mapped by EMAGE
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1242/dev.01219] [ PMID:15201223] Kurokawa D, Takasaki N, Kiyonari H, Nakayama R, Kimura-Yoshida C, Matsuo I, Aizawa S 2004 Regulation of Otx2 expression and its functions in mouse epiblast and anterior neuroectoderm. Development (131):3307-17
 [ PMID:8575305] Oliver G, Mailhos A, Wehr R, Copeland NG, Jenkins NA, Gruss P 1995 Six3, a murine homologue of the sine oculis gene, demarcates the most anterior border of the developing neural plate and is expressed during eye development. Development (121):4045-55
Links:MGI:3056068 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI