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EMAGE:132

Bmp4 bone morphogenetic protein 4 ( MGI:88180)
TS09 (6.5 dpc)
in situ hybridisation

Data Images
EMAGE:132
Figure 7D of Perea-Gomez et al., 2001 [PMID:11171400] . Copyright: This image is from Development and is displayed with the permission of the Company of Biologists Ltd. who owns the copyright.

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Expression Pattern Description
Spatial Annotation:
EMAGE:132Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
132_wholemount_strong_3D_1.wlz
132_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:132_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: one star
Text Annotation:
StructureLevelPatternNotes
extraembryonic ectoderm
detected detected
regionalExpression is detected in the distal extra-embryonic ectoderm cells.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:1274779
Entity Detected:Bmp4, bone morphogenetic protein 4 ( MGI:88180)
Notes:The probe used in this study by Perea-Gomez et al., 2001 [PMID:11171400] is indicated as that used by Winnier et al., 1995 [PMID:7657163] which is of undefined sequence.
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Age:6.5 dpc
Theiler Stage:TS09
Mutations:none (wild-type)
Preparation:wholemount
Procedures
Fixation:4% paraformaldehyde
General Information
Authors:Perea-Gomez et al., 2001 [PMID:11171400] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:11171400] Perea-Gomez A, Lawson KA, Rhinn M, Zakin L, Brulet P, Mazan S, Ang SL 2001 Otx2 is required for visceral endoderm movement and for the restriction of posterior signals in the epiblast of the mouse embryo. Development (128):753-65
 [ doi:10.1101/gad.9.17.2105] [ PMID:7657163] Winnier G, Blessing M, Labosky PA, Hogan BL 1995 Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse. Genes Dev (9):2105-16
Links:MGI:1930292 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI