EMAGE mouse gene expression spatial database

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EMAGE:13697

Lztr1 leucine-zipper-like transcriptional regulator, 1 ( MGI:1914113)
TS23 (14.5 dpc)
in situ hybridisation

Data Images


"Pseudo-wholemount" of euxassay_019520. This image has been made by aligning and collapsing the constitutent sections. Information about the method.	euxassay_019520_01	euxassay_019520_02	euxassay_019520_03	euxassay_019520_04

euxassay_019520_05	euxassay_019520_06	euxassay_019520_07	euxassay_019520_08	euxassay_019520_09

euxassay_019520_10	euxassay_019520_11	euxassay_019520_12	euxassay_019520_13	euxassay_019520_14

euxassay_019520_15	euxassay_019520_16	euxassay_019520_17	euxassay_019520_18	euxassay_019520_19

euxassay_019520_20	euxassay_019520_21	euxassay_019520_22	euxassay_019520_23	euxassay_019520_24

View assay images:
Expression pattern clarity:
Find spatially similar wholemount expression patterns:

Expression Pattern Description

Spatial Annotation:

Annotation colour key:

	strong
	moderate
	weak
	possible
	not detected

wholemount mapping

Download individual expression domains:

13697_wholemount_strong.wlz

13697_wholemount_moderate.wlz

13697_wholemount_weak.wlz

13697_wholemount_possible.wlz

13697_wholemount_not_detected.wlz

(what is wlz format?)

Download all expression domains:

EMAGE:13697_all_domains.zip

Find spatially similar wholemount expression patterns:

EMAGE spatially similar wholemount patterns

Morphological match to the template:

Text Annotation:

Structure

Level

Pattern

Notes

vibrissa

moderate

regional

moderate expression: see section 09 21 weak expression: see section 22

olfactory cortex mantle layer

moderate

regional

moderate expression: see section 18 weak expression: see section 11 12 13 16 17 19

medulla oblongata basal plate mantle layer

strong

regional

strong expression: see section 10 11 12 18 19

facial vii ganglion

strong

regional

strong expression: see section 06 07 21 22 23 24

glossopharyngeal ix ganglion

strong

regional

strong expression: see section 09 10 20 21 22

trigeminal v ganglion

strong

regional

strong expression: see section 05 06 07 09 10 11 19 20 21 22 23 24 weak expression: see section 08

vestibulocochlear viii ganglion

strong

regional

strong expression: see section 21 22

trigeminal v nerve

moderate

regional

moderate expression: see section 11 19

dorsal root ganglion

strong

regional

strong expression: see section 10 11 13 14 19 21 moderate expression: see section 12 18 20

neural retina

strong

regional

strong expression: see section 02 03 weak expression: see section 04 24

Annotation Validation:

spatial mapping by EMAGE editor, text annotation by author

Detection Reagent

Type:	in situ hybridisation probe
Identifier:	T55098
Entity Detected:	Lztr1, leucine-zipper-like transcriptional regulator, 1 ( MGI:1914113)
Sequence:	sense strand is shown >T55098 GACAACAACATTCGCAGTGGGGAAATGTACAGGTTCCAGTTCTCTTGCTACCCTAAGTGCACACTGCACG AAGATTATGGGCGCCTATGGGAGGGCCGCCAGTTCTGTGATGTGGAGTTTGTGCTTGGTGAGAAGGAAGA GTGTGTGCAAGGCCATGTTGCCATCGTCACTGCAAGGAGCCGGTGGCTTCGTAGGAAGATCGTACAGGCT CAAGAGTGGCTGGCCCAGAAGCTAGAGGAAGATGGGGCCCTAGCTCCCAAGGAGGCCCCTGGCCCAGCTG TGGGCAGGGCACGGCCACCCCTGTTACGTGTGGCCATCCGTGAGGCTGAGGCCCGGCCATTTGAGGTGCT CATGCAGTTTCTCTACACAGACAAGATCAAGTACCCACGGAAAGGCCATGTAGAAGACGTGCTGCTCATC ATGGATGTGTATAAGTTGGCGCTGAGCTTCCAGCTGTGTCGCCTTGAGCAGCTGTGTCGGCAGTACATCG AGGCCTCTGTAGATCTGCAGAATGTTCTGGTTGTGTGTGAGAGTGCTGCCAGGCTACAGCTGGGCCAGCT CAAGGAGCATTGCCTGAACTTCATAGTGAAGGAATCCCACTTCAATCAGGTGATCATGATGAAGGAGTTT GAGCGCCTCTCATCCCCACTGATTGTAGAGATAGTTCGTCGGAAGCAGCAGCCGCCCCCTCGCACACCCT CCGATCAGCCTGTGGACATTGGCACATCTCTGATCCAAGACATGAAGGCTTACCTGGAGGGAGCAGGCTC GGAGTTCTGTGACATCACACTACTGCTAGATGGCCAGCCACGGCCAGCCCACAAAGCCATCCTAGCTGCC CGTTCTAGCTACTTTGAGGCCATGTTTCGGTCGTTCATGCCAGAGGACGGGCAGGTGAACATCTCCATTG GGGAGATGGTTCCCAGCAGACAGGCCTTCGAGTCCATGCTACGCTACA
Notes:	The probe template was PCR amplified from E14.5 mouse embryo cDNA using gene specific primers. Forward Primer - name:unspecified, sequence:GACAACAACATTCGCAGTGG; Reverse Primer - name:unspecified, sequence:TGTAGCGTAGCATGGACTCG. The reverse primer contains a 5' extension containing an unspecified RNA polymerase binding site (this extension is not shown in the primer sequence listed here). Anti-sense probe was transcribed from the PCR amplified template using unspecified polymerase.
Chemistry:	RNA
Strand:	antisense
Label:	digoxigenin

Specimen

Organism:	mouse
Strain:	C57BL/6
Age:	14.5 dpc
Theiler Stage:	TS23
Mutations:	none (wild-type)
Preparation:	section

Procedures

Fixation:	none
Embedding:	cryosection (OCT)
Staining procedure:	alkaline phosphatase + NBT/BCIP

General Information

Authors:	Dr. Graciana Diez-Roux, Prof. Gregor Eichele, Prof. Richard Baldock, Dr. Duncan Davidson, Prof. Stylianos Antonarakis, Dr. Marie Laure Yaspo, Prof. Salvador Martinez Perez, Dr. Pascal Dolle, Dr. David Tannahill, Prof. Pier Paolo Di Fiore, Mr. Stefan Kruse, Mr. Paolo Sarmientos, Dr. Uwe Radelof, Prof. Andrea Ballabio.
Principal investigator:	Professor Andrea Ballabio, Fondazione Telethon, TIGEM Instituto di Genetica e Medicina, Via Pietro Castellino 111 80131, Napoli, Italy 80131
Submitted by:	EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:	screen
References:	[ doi:10.1371/journal.pbio.1000582] [ PMID:21267068] Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, et al 2011 A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo PLoS Biol (9)
Links:	EMAGE:13699 same embryo
	EMAGE:13698 same embryo
	EurExpress:euxassay_019520 same experiment
	MGI:4826048 same experiment
	Ensembl same gene
	Allen Brain Atlas same gene
	BioGPS same gene
	International Mouse Knockout Project Status same gene
	GEISHA Chicken ISH Database same gene
	EMBL-EBI Gene Expression Atlas same gene
	BrainStars same gene
	ViBrism same gene
Data Source