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EMAGE:167

Gli2 GLI-Kruppel family member GLI2 ( MGI:95728)
TS17 (10.5 dpc)
in situ hybridisation

Data Images
EMAGE:167 EMAGE:167
Fig 3D, Bai & Joyner, 2001 [PMID:11748151] . Copyright: This image is from Development and is displayed with permission of The Company of Biologists Ltd. who owns the copyright. Fig 3C, Bai & Joyner, 2001 [PMID:11748151] . Copyright: This image is from Development and is displayed with permission of The Company of Biologists Ltd. who owns the copyright.

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Spatial mapping was only done using the data in image D as the small size of image C precluded spatial mapping. Text annotation is by the GXD.
Expression Pattern Description
Spatial Annotation:
EMAGE:167Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
167_wholemount_strong_3D_1.wlz
167_wholemount_moderate_3D_1.wlz
167_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:167_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: one star
Text Annotation:
StructureLevelPatternNotes
hindlimb bud ectoderm
detected detected
Expression is present throughout the limb bud, except in the zone of polarizing activity.
neural tube
detected detected
regionalExpression is present throughout the spinal cord, except in the floor plate
neural tube floor plate
not detected not detected
Expression is present throughout the spinal cord, except in the floor plate
hindlimb bud mesenchyme
detected detected
regionalExpression is present throughout the limb bud, except in the zone of polarizing activity.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:12279
Entity Detected:Gli2, GLI-Kruppel family member GLI2 ( MGI:95728)
Notes:The probe used in this study by Bai & Joyner, 2001 [PMID:11748151] , was originally described by Hui et al., 1993 [PMID:8150204] as a "partial cDNA spanning sequences from 480 bp 5' to the zinc finger domain to the middle of the fourth zinc finger".
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Age:10.5 dpc
Theiler Stage:TS17
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Bai & Joyner, 2001 [PMID:11748151] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:11748151] Bai CB, Joyner AL 2001 Gli1 can rescue the in vivo function of Gli2. Development (128):5161-72
 [ doi:10.1006/dbio.1994.1097] [ PMID:8150204] Hui CC, Slusarski D, Platt KA, Holmgren R, Joyner AL 1994 Expression of three mouse homologs of the Drosophila segment polarity gene cubitus interruptus, Gli, Dev Biol (162):402-13
Links:MGI:2158427 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI