EMAGE mouse gene expression spatial database

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EMAGE:21507

Dner delta/notch-like EGF-related receptor ( MGI:2152889)
TS23 (14.5 dpc)
in situ hybridisation

Data Images


"Pseudo-wholemount" of euxassay_001241. This image has been made by aligning and collapsing the constitutent sections. Information about the method.	euxassay_001241_01	euxassay_001241_02	euxassay_001241_03	euxassay_001241_04

euxassay_001241_05	euxassay_001241_06	euxassay_001241_07	euxassay_001241_08	euxassay_001241_09

euxassay_001241_10	euxassay_001241_11	euxassay_001241_12	euxassay_001241_13	euxassay_001241_14

euxassay_001241_15	euxassay_001241_16	euxassay_001241_17	euxassay_001241_18	euxassay_001241_19

euxassay_001241_20	euxassay_001241_21	euxassay_001241_22	euxassay_001241_23

View assay images:
Expression pattern clarity:
Find spatially similar wholemount expression patterns:

Expression Pattern Description

Spatial Annotation:

Annotation colour key:

	strong
	moderate
	weak
	possible
	not detected

wholemount mapping

Download individual expression domains:

21507_wholemount_strong.wlz

21507_wholemount_moderate.wlz

21507_wholemount_weak.wlz

21507_wholemount_possible.wlz

21507_wholemount_not_detected.wlz

(what is wlz format?)

Download all expression domains:

EMAGE:21507_all_domains.zip

Find spatially similar wholemount expression patterns:

EMAGE spatially similar wholemount patterns

Morphological match to the template:

Text Annotation:

Structure

Level

Pattern

Notes

limb

strong

regional

strong expression: see section 1 2 3 4 5 0 1 2 3

vertebral axis musculature

strong

regional

strong expression: see section 1 2 3 4 5 6 7 8 9 0 1 2 3 4 5 6 7 8 9 0 1 2 3

foregut-midgut junction

moderate

regional

moderate expression: see section 6 7 8 9 0 1 2 3 4

diencephalon lateral wall mantle layer

moderate

homogeneous

moderate expression: see section 7 8 9 0 1 2 3 4 5 6 7 8

diencephalon lateral wall marginal layer

moderate

homogeneous

moderate expression: see section 7 8 9 0 1 2 3 4 5 6 7 8

telencephalon mantle layer

moderate

homogeneous

moderate expression: see section 1 2 3 4 5 6 7 8 9 0 1 2 3 4 5 6 7 8 9 0 1 2 3

telencephalon marginal layer

moderate

homogeneous

moderate expression: see section 1 2 3 4 5 6 7 8 9 0 1 2 3 4 5 6 7 8 9 0 1 2 3

medulla oblongata alar plate mantle layer

moderate

homogeneous

moderate expression: see section 7 8 9 0 1 2 3 4 5 6 7 8

medulla oblongata basal plate mantle layer

moderate

homogeneous

moderate expression: see section 7 8 9 0 1 2 3 4 5 6 7 8

metencephalon rest of alar plate mantle layer

moderate

homogeneous

moderate expression: see section 4 5 6 7 8 9 0 1 2 3 4 5 6 7 8 9 0 1 2

metencephalon rest of alar plate marginal layer

moderate

homogeneous

moderate expression: see section 3 4 5 6

metencephalon rest of alar plate ventricular layer

moderate

homogeneous

moderate expression: see section 3 4 5 7

pons mantle layer

moderate

homogeneous

moderate expression: see section 6 7 8 9 0 1 2 3 4 5 6 7 8 9 0

pons ventricular layer

moderate

homogeneous

moderate expression: see section 7

facial vii ganglion

strong

regional

strong expression: see section 4 5 6 0 1 2

glossopharyngeal ix ganglion

strong

regional

strong expression: see section 6 7 8 9 8 9 0

trigeminal v ganglion

strong

regional

strong expression: see section 3 4 5 6 7 8 9 8 9 0 1 2 3

vestibulocochlear viii ganglion

strong

regional

strong expression: see section 5 6 7 8 9 8 9 0

cervico-thoracic ganglion

moderate

regional

moderate expression: see section 1 7

cervical ganglion

moderate

regional

moderate expression: see section 0 1 2

thoracic ganglion

moderate

regional

moderate expression: see section 0 1 2 3 4 5 6

dorsal root ganglion

moderate

regional

moderate expression: see section 8 9 0 1 6 7 8 9

cornea stroma

strong

regional

strong expression: see section 1 2 3 3

nasal cavity olfactory epithelium

moderate

regional

moderate expression: see section 8 9 0 1 2 3 4 5 6 7 8 9

tongue muscle

moderate

regional

moderate expression: see section 1 2 3 4 5 6

stomach

moderate

regional

moderate expression: see section 1 2 3 4 5 6 7 8

hindgut

moderate

regional

moderate expression: see section 1 2 3 4

midgut

moderate

regional

moderate expression: see section 5 6 7 8 9 0 1 2 3 4 5 6

lower jaw mesenchyme

moderate

regional

moderate expression: see section 1 2 3 4 5 6 7 8 9 0 1 2 3 4 5 6 7 8 9 0 1 2 3

upper jaw mesenchyme

moderate

regional

moderate expression: see section 3 4 5 6 7 1 2 3 5 0 1 2 3

glans of male genital tubercle

moderate

regional

moderate expression: see section 0 1 2 3 4 5 6

tail

strong

regional

strong expression: see section 1 2 3 4 5

Annotation Validation:

spatial mapping by EMAGE editor, text annotation by author

Detection Reagent

Type:	in situ hybridisation probe
Identifier:	T5394
Entity Detected:	Dner, delta/notch-like EGF-related receptor ( MGI:2152889)
Sequence:	sense strand is shown >T5394 GTCAGGCCGGTCCCGCTGCGGTTTCACAGATTCTGCGCCAAGAGGTCGCGAGTGGCAGCTGCGAGCCATC TGAAGCGATCTCTTCAGGCTGCCGGGGCCTCTCCATTCACTTTCTACCCCAGCATCACCTCTCTCTCCTC TCTCAGCCGACGGCTCCCACCTCTGTGCCATCCTGCCTTCCTTTGGACACACCCACGACTCTGACCCCTT AAGGCTGGGGACCGAAGACAGCCTTCTTGCAACTTGCTGAGACGCGGAGCAGAAGGGTTCCCATCCCGGG TCCTCCAGCCGGGAGCCCAGCCTCCGTGGGCCCCGCCCCCGGCCCCGCCCGCGGTTGCCCGGGGAACCAC GGGCTCCCGCAGCTGCAGGAGGCGTCCGGTCCCGCTGAGCAGCACTAGCCGCTGGCGCCGCTGCCACCGC CATCTCCGCCGCTAGCAGCGCCGCCGTCACCGCGCCCAGCTCCTCTCCAGCTTCTGCGTTCTCTCCGCTC GCTATGCCTCCCCGCCGCGCCCAGGCGCCCGGTGCCCCGCTGCTGCCCGTGCTGGCCCTGCTGCCCCTGC TGCTGGGTGCTGGGCCCCAAAGCGGCTGCTTGGCTAGCCCGGTGTCCGCCGCGCCCCTGCCTGCTCCGGG ACCGTGCGCCTCCCAGCCCTGTCGGAACGGGGGCGTGTGCACTCCGCGTTCGGTGACCGACCAAGAGCAC CCTGCGGCCGATGCTGAGCCCCGCTACAGCTGCACCTGTCCCGCTGGGGTCTCTGGCACCTATTGTCAGT TTGTTGCAGATCCTTGTGCCAGCAACCCTTGTCACCATGGTAACTGCAGCAGCAGCAGCAGCAGCAGCAG CGACAGCTACCTCTGCATTTGCAACGACGGCTATGAAGGTCTTAACTGTGAACAACCACTTCCCAGTATT CCAACCTCTGGCTGGACAGAGTCCACGGCACCCAGACAGCTTCAGCCTGTCCCCGCCACCCAGGAGCCTG ACATAATCCTGCCCCGCTCTCAGGCAACCGTGACACTGCCAACTTGGCAGCCAAAAACAGGGCAGAAAGT TGTAGAAATGAAATGGGATCAAGTAGAGGTGGTCCCTGATGTTGCCTGTGGGAATGCCAGTTCCAACAAC TCTGCGGGTGGCCGCCTAGTGTCTTTTGAAGTGCCACAGAACACCTCTGTAAAGATTCGGCAGGATGCCA ATTCTTTGCTGATCTTGCTGTGGAAGGTCACAGCCACAGGCTTTCAACAGTGTTCCCTCATAGATGGTCG AAGTGTGACACCCCTCCAGGCTCCAGGGGGCCTTGTCCTGCTAGAGGAGATGCTGGCCTTGGGACCCAAC CACTTCATTGGTTTTGTGAATGACTCTGTTGCTAAATCCATTGTGGCTTTGCGTTTAACACTTGTGGTGA AGGCTAGCAACTGTGTTCCGGGGGACAGCCACTCAAATGACTTAGAGTGTTCGGGAAAAGGAAAATGTGC CACGAAGCCATCAGAGGCAACCTTTTCCTGCACCTGCCAGGACCAGTACATTGGCACCTTCTGTGAAGAA TTTGATGCCTGCCAGAGGAAACCCTGCCAGAATGAGGCGAGCTGTATTGATGCAAATGAGAAGCAGGATG GGAGCAATTTCACTTGCCTTTGTCTTCCAGGTTATACTGGAGAGCTTTGCCAGTCCAAGATTGATTACTG TGTCCTAGACCCATGCAGAAATGGAGCCACATGTGTGTCCAGCCTCAGCGGGTTCACCTGCCAGTGTCTG GAAGGGTACTTCGGCTCCGCTTGTGAAGAGAAGGTGGACCCTTGCATGTCCTCTCCATGCCAGAACAATG GCACTTGCTACGTGGATGGCGTGCATTTCACCTGCAGCTGCAGCCCAGGCTTCACAGGGCCTACGTGTGC CCAGCTGGTGGACTTCTGCGCCCTCAGTCCGTGTGCTCATGGCATGTGCCGTAGCGTGGGCACCAGCTAC AAGTGCCTCTGCGATCCAGGTTACCATGGCCTCTACTGTGAGGAGGAATACAATGAGTGCCTGTCGGCCC CTTGCCTGAATGCCGCCACCTGCCGGGACCTCATCAATGGCTATGAGTGTGTGTGCCTGGCAGAATATAA AGGAACACACTGCGAACTGTACAAGGACCCCTGTGCTAACATCAGCTGTCTGAATGGAGGTACCTGTGAC AGCGAGGGGCTGAATGGCACGTGCATCTGTGCACCCGGGTTCACAGGTGAAGAGTGTGACATTGACATCA ATGAATGTGATAGTAACCCATGTCATCATGCTGGAACCTGCTTGGACCAGCCCAATGGTTACACCTGCCA CTGTCCTCATGGCTGGGTGGGAGCAAACTGTGAAATCCACCTGCAGTGGAAGTCTGGGCACATGGCCGAG AGCCTCACCAACATGCCTCGGCACTCCCTCTACATCATCATCGGAGCCCTCTGCGTCGCCTTCATCCTCA TGCTCATCATCCTGATTGTGGGCATCTGCCGCATCAGCCGCATCGAGTACCAGGGCTCCTCCCGGCCAGC CTATGAGGAGTTCTACAACTGCCGCAGCATTGACAGTGAGTTCAGCAATGCCATCGCATCCATCCGGCAT GCCAGGTTTGGGAAGAAGTCTCGGCCTGCCATGTACGACGTGACTCCCATTGCCTACGAGGATTACAGTC CCGATGACAAACCCTTGGTCACACTGATTAAAACAAAAGATTTGTAATCTTTTTTGGATTATTTTTCAAA AACATATGAGATATTAAGATCGTTTAAATATTTTTAAGAAAATTAAAAAGCTTAAGAGATGTAAAATGTT AGCTGCTCAAGAGTTTTCAGTAGACTATCGAGGAACTAATTTTCTGCAGCTTTTAGTTTAAAAAAACAGT ATTTTAAAAAAAACCAGAATTTGTGAAATCCGTAGACCATGTTTTAATGTACTTTCAGCTCTCAACACTG TATACTTCAACAAGGATGGGCTTTTTTGACAGTAGACCCATCATAAAACCCAGATGGACTTCTGTGGTTG TTACAGAATAAACCTTATGTAGGAAGAGTTTCTTTTGATGTGTGATGCCGGCTTTCTGAGTAGAGTTAGG AAAATAAATAGAGTATGATGCATAATTCAGTATAATCGTTACTTAATATGACGTGGCGTCCGAGATGTTT GTTTTGTGAAAAAAGAAAACTAGTTAAATTTATTATTCCTAGCCTGAATGGAATTAGCCTCTTTCTTATT CTGTGCATGGGTAACTTATTTTCTGCACTGTTCTGTTGAACTCTGAGGAAATGTCGTTCCTTCCAGTTTG TTTGAGTCATTTTTTTTGTATCAGTCCTTGAACTTGACCTTGTAAACATAAACAAGGAAAGAGTCTAGGG AGGCAAATAGCGATCAGTTTCAACCTACAGTTTTTCCTTTAAAAGTCAAGCATTTTTCTTTTTAATTGTG AGTGGACTAAATTATGTTGCAGGTGTTTCTTGCTAAGAGGTAGTGACATGTAAGAGGTGCCAGTCCCTTC TGTAGTGTTTCTTAGAGTGCACATTTATTTATACCCAAGACAATTTTTTGTGGCTGTATTTGATTGATAT GTGCTTCTTATGATTCTTGCTAATTTCAAAGAATATTGAATAAACGTTAGCAGGTCGAGGACAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAA
Notes:	The probe template was PCR amplified from IMAGE:5365190 using vector (pCMV-SPORT6) specific primers. Forward Primer - name:RZPD T7, sequence:TAATACGACTCACTATAGGG; Reverse Primer - name:RZPD sp6, sequence:ATTTAGGTGACACTATAG. Anti-sense probe was then transcribed from the PCR amplified template using Sp6 polymerase. EMAGE Editor's Note: the probe sequence indicated here was given by the EURExpress Consortium and has been checked using a computational method whereby a BLAST comparison was made against the full insert sequence of IMAGE:5365190 which was retrieved directly from NCBI.
Chemistry:	RNA
Strand:	antisense
Label:	digoxigenin

Specimen

Organism:	mouse
Strain:	C57BL/6
Age:	14.5 dpc
Theiler Stage:	TS23
Mutations:	none (wild-type)
Preparation:	section

Procedures

Fixation:	none
Embedding:	cryosection (OCT)
Staining procedure:	alkaline phosphatase + NBT/BCIP

General Information

Authors:	Dr. Graciana Diez-Roux, Prof. Gregor Eichele, Prof. Richard Baldock, Dr. Duncan Davidson, Prof. Stylianos Antonarakis, Dr. Marie Laure Yaspo, Prof. Salvador Martinez Perez, Dr. Pascal Dolle, Dr. David Tannahill, Prof. Pier Paolo Di Fiore, Mr. Stefan Kruse, Mr. Paolo Sarmientos, Dr. Uwe Radelof, Prof. Andrea Ballabio.
Principal investigator:	Professor Andrea Ballabio, Fondazione Telethon, TIGEM Instituto di Genetica e Medicina, Via Pietro Castellino 111 80131, Napoli, Italy 80131
Submitted by:	EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:	screen
References:	[ doi:10.1371/journal.pbio.1000582] [ PMID:21267068] Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, et al 2011 A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo PLoS Biol (9)
Links:	EurExpress:euxassay_001241 same experiment
	EMAGE:21512 same embryo
	EMAGE:21509 same embryo
	EMAGE:21511 same embryo
	EMAGE:21510 same embryo
	EMAGE:21508 same embryo
	Ensembl same gene
	Allen Brain Atlas same gene
	BioGPS same gene
	International Mouse Knockout Project Status same gene
	GEISHA Chicken ISH Database same gene
	EMBL-EBI Gene Expression Atlas same gene
	BrainStars same gene
	ViBrism same gene
Data Source