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EMAGE:235

Foxa2 forkhead box A2 ( MGI:1347476)
TS10 (Late streak Downs & Davies)
in situ hybridisation

Data Images
EMAGE:235 EMAGE:235
Figure 1A of Kinder et al., 2001 [PMID:11566865] . Copyright: This image is from Development and is displayed with the permission of the Company of Biologists Ltd. who owns the copyright. Figure 1A of Kinder et al., 2001 [PMID:11566865] . This embryo is mid-streak and was not spatially mapped. Copyright: This image is from Development and is displayed with the permission of the Company of Biologists Ltd. who owns the copyright.

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Both embryos below are TS10 yet the embryo shown on the left is 'late streak' and has been spatially mapped in this EMAGE entry to the EMAP TS10 model (also late streak stage) whereas the embryo on the right is 'mid-streak' and therefore has not been spatially mapped to the EMAP TS10 (late streak) model. Anterior is to the left in both images.
Expression Pattern Description
Spatial Annotation:
EMAGE:235Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
235_wholemount_strong_3D_1.wlz
235_wholemount_weak_3D_1.wlz
235_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:235_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
embryo ectoderm
detected detected
regionalExpression is detected in the prospective foregut endoderm, the axial mesoderm, the mesoderm and ectoderm of the prospective cranial region and is shifted distally with the extension of the primitive streak.
embryo endoderm
detected detected
regionalExpression is detected in the prospective foregut endoderm, the axial mesoderm, the mesoderm and ectoderm of the prospective cranial region and is shifted distally with the extension of the primitive streak.
embryo mesoderm
detected detected
regionalExpression is detected in the prospective foregut endoderm, the axial mesoderm, the mesoderm and ectoderm of the prospective cranial region and is shifted distally with the extension of the primitive streak.
primitive streak
detected detected
regionalExpression is detected in the prospective foregut endoderm, the axial mesoderm, the mesoderm and ectoderm of the prospective cranial region and is shifted distally with the extension of the primitive streak.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:2154937
Entity Detected:Foxa2, forkhead box A2 ( MGI:1347476)
Notes:The Foxa2 (HNF3-beta) probe used in this study by Kinder et al., 2001 [PMID:11566865] is of undefined sequence.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:Late streak Downs & Davies
Theiler Stage:TS10
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Kinder et al., 2001 [PMID:11566865] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:11566865] Kinder SJ, Tsang TE, Wakamiya M, Sasaki H, Behringer RR, Nagy A, Tam PP 2001 The organizer of the mouse gastrula is composed of a dynamic population of progenitor cells for the axial mesoderm. Development (128):3623-34
 [ PMID:8269852] Downs KM, Davies T 1993 Staging of gastrulating mouse embryos by morphological landmarks in the dissecting microscope. Development (118):1255-66
Links:MGI:2154955 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE