Quicksearch Help

(Click the icon to keep this page displayed.)

EMAGE:242

Notch1 Notch gene homolog 1 (Drosophila) ( MGI:97363)
TS17 (10.5 dpc)
in situ hybridisation

Data Images
EMAGE:242
Fig 5D Del Amo et al, 1992 [PMID:1425352] . Copyright: This image is from Development and is displayed with permission of The Company of Biologists Ltd. who owns the copyright.

Expression pattern clarity: no stars
Notes:
Abbreviations: dr, condensing dorsal root ganglion; ms, mesonephric tubules; vh, ventral horn of the spinal cord; vz, ventricular zone, arrow indicates endothelial cells lining the intersomitic blood vessels.
Expression Pattern Description
Text Annotation:
StructureLevelPatternNotes
dorsal root ganglion
detected detected
future spinal cord
detected detected
cardiovascular system
detected detected
regionalExpression is detected in intersomitic blood vessels (see arrows in figure).
mesonephros
detected detected
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:2445989
Entity Detected:Notch1, Notch gene homolog 1 (Drosophila) ( MGI:97363)
Sequence:sense strand is shown

>MGI:2445989
AGTGCCGAATGTGAGTGGGATGGCCTAGACTGTGCTGAGCATGTACCCGAGCGGCTGGCAGCGGGCACCC
TGGTCCTGGTGGTGCTGCTTCCACCCGACCAGCTACGGAACAACTCCTTCCACTTTCTGCGGGAGCTCAG
CCACGTGCTGCACACCAACGTGGTCTTCAAGCGTGATGCGCAAGGCCAGCAGATGATCTTCCCGTACTAT
GGCCACGAGGAAGAGCTGCGCAAGCACCCAATCAAGCGCTCTACAGTGGGTTGGGCCACCTCTTCACTGC
TTCCTGGTACC
nt 4729 - nt 5019 of Z11886.1
Notes:The probe used in this study by Del Amo et al, 1992 [PMID:1425352] is described as a "EcoRI - KpnI fragment" which "encodes the last 13 amino acids of the third Notch/lin-12 repeat, as well as the succeeding 84 amino acids of the Motch gene".See Fig 1A therein for sequence.
Chemistry:RNA
Strand:antisense
Label:S35
Specimen
Organism:mouse
Strain:C57BL/6
Age:10.5 dpc
Theiler Stage:TS17
Mutations:none (wild-type)
Preparation:section
Procedures
Fixation:4% paraformaldehyde
Embedding:paraffin
Staining procedure:autoradiography
General Information
Authors:Del Amo et al, 1992 [PMID:1425352] Indexed by GXD.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:1425352] Del Amo FF, Smith DE, Swiatek PJ, Gendron-Maguire M, Greenspan RJ, McMahon AP, Gridley T 1992 Expression pattern of Motch, a mouse homolog of Drosophila Notch, suggests an important role in early postimplantation mouse development. Development (115):737-44
Links:MGI:1333991 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI