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EMAGE:252

Vax1 ventral anterior homeobox containing gene 1 ( MGI:1277163)
TS12 (8.0 dpc)
in situ hybridisation

Data Images
EMAGE:252 EMAGE:252 EMAGE:252
Fig 3A Hallonet et al, 1998 [PMID:9636075] . Copyright: This image is from Development and is diplayed with the permission of the Company of Biologists Ltd. who owns the copyright. Fig 3B Hallonet et al, 1998 [PMID:9636075] . Copyright: This image is from Development and is diplayed with the permission of the Company of Biologists Ltd. who owns the copyright. Fig 3C Hallonet et al, 1998 [PMID:9636075] . Copyright: This image is from Development and is diplayed with the permission of the Company of Biologists Ltd. who owns the copyright.

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Find spatially similar expression patterns: Find spatially similar patterns
Notes:
The wholemount embryo shown in A and B was vibratome sectioned to produce the lateral parasagittal section in C. Abbreviations: FB - forebrain, MB - midbrain, NP - Neural plate epithelium, pOP - prospective olfactory placode ectoderm, Mch - cephalic mesenchyme. Scale bar : 100 microns. The data in images A and C have been spatially mapped in this EMAGE entry.
Expression Pattern Description
Spatial Annotation:
EMAGE:252EMAGE:252EMAGE:252Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
3D mapping3D context moviewholemount mapping

View mapped 3D expression image EMAGE genex expression entry
Download individual expression domains:
252_wholemount_strong_3D_2.wlz
252_wholemount_notDetected_3D_2.wlz
252_voxel_strong_3D_1.wlz
252_voxel_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:252_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Find spatially similar expression patterns: EMAGE spatially similar patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
embryo
detected detected
regionalExpression is restricted to the anterior end of the embryo
future spinal cord neural plate
detected detected
regionalExpression is restricted to the anterior border of the neural plate. Transcription occurs in the anterior part of the telencephalic neural plate, anterior neural ridge, and in the prospective olfactory placode ectoderm. Expression does not contact the cephalic mesenchyme, and does not extend to the hypophysial placode
neural ectoderm
detected detected
regionalTranscription occurs in the anterior part of the telencephalic neural plate, anterior neural ridge, and in the prospective olfactory placode ectoderm. Expression does not contact the cephalic mesenchyme, and does not extend to the hypophysial placode
head mesenchyme
not detected not detected
homogeneousTranscription occurs in the anterior part of the telencephalic neural plate, anterior neural ridge, and in the prospective olfactory placode ectoderm. Expression does not contact the cephalic mesenchyme, and does not extend to the hypophysial placode
surface ectoderm
detected detected
regionalTranscription occurs in the prospective olfactory placode ectoderm.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:1289531
Entity Detected:Vax1, ventral anterior homeobox containing gene 1 ( MGI:1277163)
Notes:The probe used in this study by Hallonet et al, 1998 [PMID:9636075] is called cf5 by the authors and described as a "partial cDNA clone", "containing the coding region of the mouse Vax1 homeobox". Exact sequence is not specified.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Strain:NMRI
Age:8.0 dpc
Theiler Stage:TS12
Mutations:none (wild-type)
Preparation:wholemount
Procedures
Staining procedure:NBT/BCIP
General Information
Authors:Hallonet et al, 1998 [PMID:9636075] Indexed by GXD, Spatially mapped by EMAGE
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:9636075] Hallonet M, Hollemann T, Wehr R, Jenkins NA, Copeland NG, Pieler T, Gruss P 1998 Vax1 is a novel homeobox-containing gene expressed in the developing anterior ventral forebrain. Development (125):2599-610
Links:MGI:1303377 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI