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EMAGE:281

Smad1 MAD homolog 1 (Drosophila) ( MGI:109452)
TS11 (7.25 dpc)
in situ hybridisation

Data Images
EMAGE:281 EMAGE:281
Figure 6B' of Tremblay et al., 2001 [PMID:11566864] . Copyright: This image is from Development and is displayed with the permission of the Company of Biologists Ltd. who owns the copyright. Figure 6B of Tremblay et al., 2001 [PMID:11566864] . Copyright: This image is from Development and is displayed with the permission of the Company of Biologists Ltd. who owns the copyright.

Expression pattern clarity: no stars
Notes:
Corresponding bright and darkfield images are shown below. Abbreviations used: al, allantois; am, amnion; ch, chorion; ps, primitive streak; ve, visceral endoderm.
Expression Pattern Description
Text Annotation:
StructureLevelPatternNotes
allantois mesoderm
detected detected
amnion mesoderm
detected detected
chorion mesoderm
detected detected
embryo mesoderm
detected detected
visceral extraembryonic endoderm
detected detected
homogeneous
yolk sac mesoderm
detected detected
embryo
weak weak
homogeneousExpression is stated as present in the streak and also present in the epiblast and chorion but at lower levels then the mesoderm and VE.
primitive streak
weak weak
homogeneousExpression is stated as present in the streak and also present in the epiblast and chorion but at lower levels then the mesoderm and VE.
chorion
weak weak
homogeneousExpression is stated as present in the streak and also present in the epiblast and chorion but at lower levels then the mesoderm and VE.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:2155348
Entity Detected:Smad1, MAD homolog 1 (Drosophila) ( MGI:109452)
Notes:The Madh1 (Smad1) probe used in this study by Tremblay et al., 2001 [PMID:11566864] is indicated as being described by Waldrip et al., 1998 [PMID:9529255] ie. as a "full-length cDNA". Exact end positions are not specified.
Chemistry:RNA
Strand:antisense
Label:Unspecified radioactivity
Specimen
Organism:mouse
Strain:MF1
Age:7.25 dpc
Theiler Stage:TS11
Mutations:none (wild-type)
Preparation:section
Procedures
Fixation:4% paraformaldehyde
Embedding:paraffin
Staining procedure:autoradiography
General Information
Authors:Tremblay et al., 2001 [PMID:11566864] . Indexed by GXD.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:11566864] Tremblay KD, Dunn NR, Robertson EJ 2001 Mouse embryos lacking Smad1 signals display defects in extra-embryonic tissues and germ cell formation. Development (128):3609-21
 [ doi:10.1016/S0092-8674(00)81407-5] [ PMID:9529255] Waldrip WR, Bikoff EK, Hoodless PA, Wrana JL, Robertson EJ 1998 Smad2 signaling in extraembryonic tissues determines anterior-posterior polarity of the early mouse embryo. Cell (92):797-808
Links:MGI:2155958 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE