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EMAGE:297

Wnt7a wingless-related MMTV integration site 7A ( MGI:98961)
TS24 (16 dpc)
in situ hybridisation

Data Images
EMAGE:297 EMAGE:297
Figure 6D of Dabdoub et al., 2003 [PMID:12702652] Copyright: This image is from Development and is displayed with the permission of The Company of Biologists Ltd. who owns the copyright. Figure 6E of Dabdoub et al., 2003 [PMID:12702652] Copyright: This image is from Development and is displayed with the permission of The Company of Biologists Ltd. who owns the copyright.

Expression pattern clarity: no stars
Notes:
Image annotations: (D) Whole-mount in situ hybridization for Wnt7a at E16. By this stage, expression of Wnt7a is restricted to a band of cells that extends along the length of the cochlea (arrows) from base to apex. Box indicates region illustrated in E. (E) Cross-section through the basal region of the cochlear duct at E16. Expression of Wnt7a is restricted to developing pillar cells (arrow) located directly above the spiral vessel (asterisk). Inner is towards the left (Mod - modiolus), outer is towards the right (Str - stria vascularis).
Expression Pattern Description
Text Annotation:
StructureLevelPatternNotes
cochlea
detected detected
regionalFig6D - Expression is present in a narrow band of cells that extends along the length of the cochlea from base to apex; it is probably the developing sensory epithelium.
cochlear duct
weak weak
regionalFig 6D - Weak expression is present in some cells in the apical region of the inner half of the cochlear duct. Fig 6E - Strong expression is present in the developing pillar cells located directly above the spiral vessel, an embryonic marker of the location of the developing organ of Corti.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:2655269
Entity Detected:Wnt7a, wingless-related MMTV integration site 7A ( MGI:98961)
Notes:The Wnt7a probe used in this study by Dabdoub et al., 2003 [PMID:12702652] is of undefined sequence.
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Age:16 dpc
Theiler Stage:TS24
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Dabdoub et al., 2003 [PMID:12702652] Indexed by GXD
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1242/dev.00448] [ PMID:12702652] Dabdoub A, Donohue MJ, Brennan A, Wolf V, Montcouquiol M, Sassoon DA, Hseih JC, Rubin JS, Salinas PC, Kelley MW 2003 Wnt signaling mediates reorientation of outer hair cell stereociliary bundles in the mammalian cochlea. Development (130):2375-84
Links:MGI:2655282 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE