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EMAGE:3263

Adrbk1 adrenergic receptor kinase, beta 1 ( MGI:87940)
TS12 (8.5 dpc)
in situ hybridisation

Data Images
EMAGE:3263 EMAGE:3263
Fig 1D Sefton et al, 2000 [PMID:11044616] Copyright: Reprinted with permission from Elsevier from [doi:10.1016/S0925-4773(00)00441-X] Mech Dev 98: 127-31, Sefton M; Blanco MJ; Penela P; Mayor F; Nieto MA, Expression of the G protein-coupled receptor kinase 2 during early mouse embryogenesis Copyright 2000 Fig 1E Sefton et al, 2000 [PMID:11044616] Copyright: Reprinted with permission from Elsevier from [doi:10.1016/S0925-4773(00)00441-X] Mech Dev 98: 127-31, Sefton M; Blanco MJ; Penela P; Mayor F; Nieto MA, Expression of the G protein-coupled receptor kinase 2 during early mouse embryogenesis Copyright 2000

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image annotations: The section plane of E is shown in D. al - allantois; ba - branchial arches.
Expression Pattern Description
Spatial Annotation:
EMAGE:3263Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
3263_wholemount_strong_3D_1.wlz
3263_wholemount_moderate_3D_1.wlz
3263_wholemount_weak_3D_1.wlz
3263_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:3263_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
allantois
detected detected
Expression is in the allantois
1st branchial arch mesenchyme derived from neural crest
detected detected
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:2386869
Entity Detected:Adrbk1, adrenergic receptor kinase, beta 1 ( MGI:87940)
Notes:Two Adrbk1 (GRK2) probes were used in this study by Sefton et al, 2000 [PMID:11044616] . They are described as "a NotI/SacI (540 bp) and a HindIII/SpHI (933bp) fragments subcloned from the complete mouse cDNA, which correspond to the amino and carboxy-terminal domains of the GRK2 protein, respectively". Editor's Note: it is unclear from the manuscript whether the two probes were mixed together to produce this result or if one or the other was used alone.
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Strain:BALB/c
Age:8.5 dpc
Theiler Stage:TS12
Mutations:none (wild-type)
Preparation:wholemount
Procedures
Fixation:4% paraformaldehyde
General Information
Authors:Sefton M, Blanco MJ, Penela P, Mayor F, Nieto MA (2000) [PMID:11044616] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1016/S0925-4773(00)00441-X] [ PMID:11044616] Sefton M, Blanco MJ, Penela P, Mayor F, Nieto MA 2000 Expression of the G protein-coupled receptor kinase 2 during early mouse embryogenesis. Mech Dev (98):127-31
Links:MGI:2386962 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI