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EMAGE:3264

Adrbk1 adrenergic receptor kinase, beta 1 ( MGI:87940)
TS15 (9.5 dpc)
in situ hybridisation

Data Images
EMAGE:3264 EMAGE:3264 EMAGE:3264
Fig 1F Sefton et al, 2000 [PMID:11044616] Copyright: Reprinted with permission from Elsevier from [doi:10.1016/S0925-4773(00)00441-X] Mech Dev 98: 127-31, Sefton M; Blanco MJ; Penela P; Mayor F; Nieto MA, Expression of the G protein-coupled receptor kinase 2 during early mouse embryogenesis Copyright 2000 Fig 1G Sefton et al, 2000 [PMID:11044616] Copyright: Reprinted with permission from Elsevier from [ [doi:10.1016/S0925-4773(00)00441-X] Mech Dev 98: 127-31, Sefton M; Blanco MJ; Penela P; Mayor F; Nieto MA, Expression of the G protein-coupled receptor kinase 2 during early mouse embryogenesis Copyright 2000 Fig 1H Sefton et al, 2000 [PMID:11044616] Copyright: Reprinted with permission from Elsevier from [ [doi:10.1016/S0925-4773(00)00441-X] Mech Dev 98: 127-31, Sefton M; Blanco MJ; Penela P; Mayor F; Nieto MA, Expression of the G protein-coupled receptor kinase 2 during early mouse embryogenesis Copyright 2000

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image annotations: The approximate section planes of G and H are shown in F. ba - branchial arches, pnc - premigratory neural crest, nt - neural tube.
Expression Pattern Description
Spatial Annotation:
EMAGE:3264Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
3264_wholemount_strong_3D_1.wlz
3264_wholemount_moderate_3D_1.wlz
3264_wholemount_weak_3D_1.wlz
3264_wholemount_possible_3D_1.wlz
3264_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:3264_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
1st branchial arch mandibular component mesenchyme derived from neural crest
detected detected
Transcripts were detected in the cephalic neural crest on their way towards the branchial arches, where they can be seen from 8.5 dpc
1st branchial arch maxillary component mesenchyme derived from neural crest
detected detected
Transcripts were detected in the cephalic neural crest on their way towards the branchial arches, where they can be seen from 8.5 dpc
2nd branchial arch mesenchyme derived from neural crest
detected detected
Transcripts were detected in the cephalic neural crest on their way towards the branchial arches, where they can be seen from 8.5 dpc
3rd branchial arch mesenchyme derived from neural crest
detected detected
Transcripts were detected in the cephalic neural crest on their way towards the branchial arches, where they can be seen from 8.5 dpc
head mesenchyme derived from neural crest
detected detected
Transcripts were detected in the cephalic neural crest on their way towards the branchial arches, where they can be seen from 8.5 dpc
neural tube roof plate
detected detected
regionalExpression is in trunk premigratory neural crest cells. These cells seem to downregulate expression soon after they have emigrated from the neural tube.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:2386869
Entity Detected:Adrbk1, adrenergic receptor kinase, beta 1 ( MGI:87940)
Notes:Two Adrbk1 (GRK2) probes were used in this study by Sefton et al, 2000 [PMID:11044616] . They are described as "a NotI/SacI (540 bp) and a HindIII/SpHI (933bp) fragments subcloned from the complete mouse cDNA, which correspond to the amino and carboxy-terminal domains of the GRK2 protein, respectively". Editor's Note: it is unclear from the manuscript whether the two probes were mixed together to produce this result or if one or the other was used alone.
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Strain:BALB/c
Age:9.5 dpc
Theiler Stage:TS15
Mutations:none (wild-type)
Preparation:wholemount
Procedures
Fixation:4% paraformaldehyde
General Information
Authors:Sefton M, Blanco MJ, Penela P, Mayor F, Nieto MA (2000) [PMID:11044616] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1016/S0925-4773(00)00441-X] [ PMID:11044616] Sefton M, Blanco MJ, Penela P, Mayor F, Nieto MA 2000 Expression of the G protein-coupled receptor kinase 2 during early mouse embryogenesis. Mech Dev (98):127-31
Links:MGI:2386962 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI