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EMAGE:3322

Cdx1 caudal type homeobox 1 ( MGI:88360)
TS15 (9.5 dpc)
in situ hybridisation

Data Images
EMAGE:3322
Fig 2C Prinos et al., 2001 [PMID:11784033] .Copyright. Reprinted with permission from Elsevier from [doi:10.1006/dbio.2001.0446] Dev Biol 239: 257-69, Prinos P; Joseph S; Oh K; Meyer BI; Gruss P; Lohnes D, Multiple Pathways Governing Cdx1 Expression during Murine Development. Copyright 2001

Expression pattern clarity: two stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image annotations: Arrowheads indicate the residual posterior mesoderm expression in the wild-type embryos that is lost in the vt mutants at E9.5. Arrows point to the hindgut primordia. Bars, 200 microns. Both embryos show wild-type expression of Cdx-1.
Expression Pattern Description
Spatial Annotation:
EMAGE:3322Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
3322_wholemount_strong_3D_1.wlz
3322_wholemount_moderate_3D_1.wlz
3322_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:3322_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
embryo
detected detected
regionalPosterior mesoderm expression.
limb
detected detected
hindgut
detected detected
tail
detected detected
trunk somite
detected detected
regionalExpression is in the dermomyotome.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:1345758
Entity Detected:Cdx1, caudal type homeobox 1 ( MGI:88360)
Notes:The probe used in this study by Prinos et al., 2001 [PMID:11784033] is indicated as that previously described by Meyer and Gruss, 1993 [PMID:7900985] i.e. as "encoding the 3' part of the translated region (without the homeobox)." Exact start and end points are not defined.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:9.5 dpc
Theiler Stage:TS15
Mutations:none (wild-type)
Preparation:wholemount
Procedures
Fixation:4% paraformaldehyde
Staining procedure:alkaline phosphatase
General Information
Authors:Prinos P, Joseph S, Oh K, Meyer BI, Gruss P, Lohnes D, 2001 [PMID:11784033] . Indexed by GXD, Spatially Mapped by EMAGE
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1006/dbio.2001.0446] [ PMID:11784033] Prinos P, Joseph S, Oh K, Meyer BI, Gruss P, Lohnes D 2001 Multiple pathways governing Cdx1 expression during murine development. Dev Biol (239):257-69
 [ PMID:7900985] Meyer BI, Gruss P 1993 Mouse Cdx-1 expression during gastrulation. Development (117):191-203
Links:MGI:2154436 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI