EMAGE mouse gene expression spatial database

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EMAGE:3324

Gbx2 gastrulation brain homeobox 2 ( MGI:95668)
TS12 (8.5 dpc)
in situ hybridisation

Data Images


Figure 2B of Li & Joyner, 2001 [PMID:11748135] .Copyright: This image is from Li and Joyner, Development 128:4979-91 (2001), and is displayed with the permission of The Company of Biologists Limited who owns the Copyright.

Expression pattern clarity:
Find spatially similar wholemount expression patterns:

Notes:

Anterior is towards the left. Image annotation: The arrowhead points to a region at the anterior tip of the embryo that remains Gbx2-negative in other embryos after exposure to a teratogenic dose of retinoic acid (RA).

Expression Pattern Description

Spatial Annotation:

Annotation colour key:

	strong
	moderate
	weak
	possible
	not detected

wholemount mapping

Download individual expression domains:

3324_wholemount_strong_3D_1.wlz

3324_wholemount_moderate_3D_1.wlz

3324_wholemount_weak_3D_1.wlz

3324_wholemount_possible_3D_1.wlz

3324_wholemount_notDetected_3D_1.wlz

(what is wlz format?)

Download all expression domains:

EMAGE:3324_all_domains.zip

Find spatially similar wholemount expression patterns:

EMAGE spatially similar wholemount patterns

Morphological match to the template:

Text Annotation:

Structure

Level

Pattern

Notes

embryo

detected

regional

Annotation Validation:

EMAGE Editor

Detection Reagent

Type:	in situ hybridisation probe
Identifier:	MGI:26910
Entity Detected:	Gbx2, gastrulation brain homeobox 2 ( MGI:95668)
Sequence:	sense strand is shown >MGI:26910 GGCGCCCGCCAGAGACAAGTGCGCCGGCTTCGCGCGCTCCCCAGCCGCCCGTGGGAGACGACGGACTGCA GGACGGACAGACGGACGGACGCACGCACTGCTGGTAGCTGGGCCGAGACCTGCAGACGCGAAGCGCGCGC GTTCCGACGGGCTAGCAGCCGGGAGCGGTTCCGGCGAACGCGAGGTCCCCGGCGCCCTCTCCATCCCGGG CGCACGGCCTCATCGCGCTCGGTGGCTGCACCCGTGCAGGCCGGGTATGCTGCGGGTCCTGCACTGAGGG GCGGTGGTGGTGTCTGTGCTCTGGGCACCGCTCAGCCCCTGCCCGGAGTTCCCGGTGGTACTCCCAGCGT CCGGAGGGCTTCCAGGCGGCGGCGGGACACGGGGACTTTTCGTCTCTCCCTGGCTTCTCCCGAACGCGTC TATGAGCGCAGCGTTCCCGCCGTCGCTGATGATGATGCAGCGCCCGCTGGGGAGTAGTACCGCCTTCAGC ATAGACTCGCTGATCGGCAGCCCGCCGCAGCCCAGTCCCGGCCATTTCGTCTACACCGGCTACCCCATGT TCATGCCCTACCGGCCGGTGGTGCTGCCGCCACCGCCGCCACCGCCTCCCGCGCTGCCCCAGGCAGCGCT GCAGCCCGCTCTGCCGCCCGCGCACCCTCACCACCAGATCCCCAGCCTGCCCACCGGCTTCTGCTCCAGC CTGGCGCAGGGCATGGCGCTCACCTCCACGCTCATGGCCACTCTGCCCGGCGGCTTCTCTGCGTCGCCCC AGCACCAAGAGGCGGCGGCTGCCCGCAAGTTCGCTCCACAGCCACTGCCCGGAGGCGGCAACTTCGACAA AGCCGAGGCGCTCCAAGCGGATGCGGAAGACGGCAAAGCCTTCTTGGCCAAGGAGGGCTCGCTGCTCGCT TTCTCTGCGGCCGAAGCGGTGCAGGCGTCGCTCGTCGGGGCTGTCCGAGGGCAAGGGAAAGACGAGTCAA AGGTGGAAGATGACCCGAAGGGCAAGGAGGAGAGCTTCTCTCTGGAGAGCGATGTGGATTACAGCTCAGA TGACAATTTGCCTGGTCAGACTGCTCATAAGGAAGAAGACCCCGGCCACGCACTGGAGGAGACCCCGCAG AGCGGCGGTGCAGCAGGCAGCACCACGTCCACAGGCAAGAACCGGCGGCGGCGGACTGCCTTCACCAGCG AACAGCTGCTGGAGCTGGAGAAAGAATTCCACTGCAAAAAGTACCTCTCCCTGACCGAGCGCTCACAGAT CGCCCACGCCCTCAAACTCAGCGAGGTGCAAGTAAAAATCTGGTTCCAGAACCGCCGGGCCAAGTGGAAA CGTGTCAAGGCAGGCAACGCCAATTCCAAGACGGGGGAGCCCTCTCGGAACCCCAAGATTGTCGTCCCCA TCCCTGTTCACGTTAGCAGGTTCGCTATTCGAAGTCAACACCAGCAGCTGGAGCAGGCCCGACCCTGAGG GCCCAGCCAGGGTGGACACCACCATGGAGAGGCCCTAACACCTGAAGGAACCCGTGTCAGACTCCACTGT TTAAAGCAGAACTCAGAGGCACCTCCTAGATGTGGACATCCAAGCAAATTGAGAGTATATTCATTAGACG GGCTTAAAGGGGGCTACAGCCACACCAGAAGATACACTAAATATTTATTATACAACCCTACTTTGTACAT AGATCTCTATCTAGACTGGATCTCAGCTGCAGTGTTTTGAAAGGGATAGGATCAAATCTCTCTCCTTACA CTTTCCAGATGAAACAAAACCACCACTGTACTCTGTCGCCTTCAGCGACCACCTTCCCATACGTGCCCAA AGGTAAACAGGAGACACAAGGACAAACACTGCGGTTTAACCTTCTTATTGTTATTTTTTGTTTGTTTGTT TCTATTTTGGCTTTTTGAGTTGAGTGCAGAGCAGTCGGTTGATTTTGGAGCAATCTAGAACTCTGCTCTG CTCGTTTGCTTTGCCTGGCTGTCTTTCCTGGCCTTGTATATCCTATCTGAGCCATGTCGGAAGCACGTCT CCGTTGTGTTTAATTTATTTCAATGTAGCTTATTTTCATATAAGTTATGACATTTAAACAATCTCAGTCT TGTGAATAATAAAAAAAAAGGCGAGG
	nt 1 - nt 2126 of Z48800.1
Notes:	The probe used in this study by Li & Joyner, 2001 [PMID:11748135] is indicated as that described by Bouillet et al., 1995 [PMID:8601031] i.e. a "2.1 kb Stra7/Gbx-2 cDNA". Editor's note: The 2.1kb sequence is depicted in Fig 1 therein and was submitted to GenBank by P. Bouillet (and subsequently assigned the ID Z48800).
Chemistry:	RNA
Strand:	antisense
Label:	digoxigenin

Specimen

Organism:	mouse
Age:	8.5 dpc
Theiler Stage:	TS12
Mutations:	none (wild-type)
Preparation:	wholemount

Procedures

General Information

Authors:	Li JY; Joyner AL, 2001 [PMID:11748135] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:	EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:	non-screen
References:	[ PMID:11748135] Li JY, Joyner AL 2001 Otx2 and Gbx2 are required for refinement and not induction of mid-hindbrain gene expression. Development (128):4979-91
	[ doi:10.1002/aja.1002040404] [ PMID:8601031] Bouillet P, Chazaud C, Oulad-Abdelghani M, Dolle P, Chambon P 1995 Sequence and expression pattern of the Stra7 (Gbx-2) homeobox-containing gene induced by retinoic acid in P19 embryonal carcinoma cells. Dev Dyn (204):372-82
Links:	MGI:2158708 same experiment
	Ensembl same gene
	Allen Brain Atlas same gene
	BioGPS same gene
	International Mouse Knockout Project Status same gene
	GEISHA Chicken ISH Database same gene
	EMBL-EBI Gene Expression Atlas same gene
	BrainStars same gene
	ViBrism same gene
Data Source