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EMAGE:3334

Gsx2 GS homeobox 2 ( MGI:95843)
TS20 (12.5 dpc)
in situ hybridisation

Data Images
EMAGE:3334
Figure 1E of Corbin Jet al., 2000 [PMID:11060228] .Copyright: This image is from Corbin et al., Development 127:5007-20 (2000), and is displayed with the permission of The Company of Biologists Limited who owns the Copyright.

Expression pattern clarity: two stars
Find spatially similar expression patterns: Find spatially similar patterns
Notes:
Note: LGE, lateral ganglionic eminence; MGE, medial ganglionic eminence.
Expression Pattern Description
Spatial Annotation:
EMAGE:3334EMAGE:3334Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
3D mappingspatial mapping

View mapped 3D expression image EMAGE genex expression entry
Download individual expression domains:
3334_voxel_strong_3D_1.wlz
3334_voxel_moderate_3D_1.wlz
3334_voxel_possible_3D_1.wlz
3334_voxel_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:3334_all_domains.zip
Find spatially similar expression patterns: EMAGE spatially similar patterns
Morphological match to the template: one star
Text Annotation:
StructureLevelPatternNotes
telencephalon
detected detected
regionalExpression in the lateral ganglionic eminence and medial ganglionic eminence.
telencephalon ventricular layer
detected detected
regionalRestricted to ventricular zone; no expression in subventricular zone or differentiated structures of the ventral telencephalon.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:2447759
Entity Detected:Gsx2, GS homeobox 2 ( MGI:95843)
Sequence:sense strand is shown

>MGI:2447759
CTGCCTCGGCTAACGAAGACAAGGAGATTTCCCCCTTGTAAAGGCAGAGGCTCCTTCTGCTACCTGCTCC
CGGTACCCTGCCCTCCTCCTCCCCATCAGCACAGGGACCAAAGTTCTAGTCCATTGCCCTCATTCCACCT
GGAAAAGAAACTCTGAAAAGTCCGGGGAATTCAATGCCGGGCCCGACTTTGAAGCTAGCTCCTCTTTATC
TGGGATTCCACTCAGTTACGGATTGGTTTTTTGTTTGCTTTTTTGTTGTTTTTAATGTAAATATCTAGAA
TTCTAACCAGTCTCATATATCAGGAAAAACCAGGGTTGATTAAAGTTTAACACTGTATGGGGGGAGGGGT
TGGTTGAAGACGCATGCCATTTGCCCCCCTGTCTTTTCAGAACTTGATGAGAAGAGGGGTTTCTTTATTG
TTTTTGTTGTTGTTTTAAAATGAAATCATTGAAGTTGCCAT
nt 1038 - nt 1498 of S79041.1
Notes:The probe used in this study by Corbin et al., 2000 [PMID:11060228] is indicated as that described by Hsieh-Li et al., 1995 [PMID:7619729] ie. "a 460-bp PCR product fragment of the Gsh-2 cDNA (bases 1038-1498), which does not contain homeobox sequences". Editor's note: S79041.1 is the sequence submitted to GenBank from Hsieh-Li et al and it is the same sequence as shown in Fig 1 of Hsieh-Li et al., 1995 [PMID:7619729] .
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:12.5 dpc
Theiler Stage:TS20
Mutations:none (wild-type)
Preparation:section
Procedures
Fixation:4% paraformaldehyde
Embedding:cryosection
General Information
Authors:Corbin JG; Gaiano N; Machold RP; Langston A; Fishell G, 2000 [PMID:11060228] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:11060228] Corbin JG, Gaiano N, Machold RP, Langston A, Fishell G 2000 The Gsh2 homeodomain gene controls multiple aspects of telencephalic development. Development (127):5007-20
 [ doi:10.1016/0925-4773(94)00334-J] [ PMID:7619729] Hsieh-Li HM, Witte DP, Szucsik JC, Weinstein M, Li H, Potter SS 1995 Gsh-2, a murine homeobox gene expressed in the developing brain. Mech Dev (50):177-86
Links:MGI:2153157 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI