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EMAGE:3353

Arc activity regulated cytoskeletal-associated protein ( MGI:88067)
TS11 (LS (late streak) Downs & Davies)
in situ hybridisation

Data Images
EMAGE:3353
Fig 4C Liu et al, 2000. [PMID:10727859] .Copyright: Reprinted with permission from Elsevier from [doi:10.1016/S0925-4773(99)00340-8] Mech Dev 92: 207-15, Liu D; Bei D; Parmar H; Matus A, Activity-regulated, cytoskeleton-associated protein (Arc) is essential for visceral endoderm organization during early embryogenesis. Copyright 2000

Expression pattern clarity: one star
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image annotations: c, chorion; ep, epiblast; ve, visceral endoderm; a, allantois. Scale bar = 200 microns. Editor's Note: The authors state that this is a 'late-streak' embryo, however it has morphological features indicative of TS11 and not TS10 and has thus been entered into EMAGE as such.
Expression Pattern Description
Spatial Annotation:
EMAGE:3353Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
3353_wholemount_strong_3D_1.wlz
3353_wholemount_moderate_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:3353_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
embryo
detected detected
Expression is ubiquitous.
extraembryonic component
detected detected
Expression is ubiquitous.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:3033342
Entity Detected:Arc, activity regulated cytoskeletal-associated protein ( MGI:88067)
Notes:The probe used in this study by Liu et al, 2000. [PMID:10727859] is described as "An Arc riboprobe covering the entire open reading frame". Editor's note: exact start and end points of the probe are not defined.
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Strain:C57BL/6
Age:LS (late streak) Downs & Davies
Theiler Stage:TS11
Mutations:none (wild-type)
Preparation:wholemount
Procedures
Fixation:4% paraformaldehyde
General Information
Authors:Liu D; Bei D; Parmar H; Matus A, 2000. [PMID:10727859] . Indexed by GXD, Spatially mapped by EMAGE
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1016/S0925-4773(99)00340-8] [ PMID:10727859] Liu D, Bei D, Parmar H, Matus A 2000 Activity-regulated, cytoskeleton-associated protein (Arc) is essential for visceral endoderm organization during early embryogenesis. Mech Dev (92):207-15
Links:MGI:3033346 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI