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EMAGE:3370

Msx2 homeobox, msh-like 2 ( MGI:97169)
TS18 (10.5 dpc)
in situ hybridisation

Data Images
EMAGE:3370
Figure 8A of Ishii et al., 2003 [PMID:14597577] . Copyright: This image is from Ishii et al., Development 130:6131-6142 (2003), and is displayed with the permission of The Company of Biologists Limited who owns the Copyright.

Expression pattern clarity: two stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Note: e, eye; fn, frontonasal process. Arrowhead: site of the frontal bone primordium.
Expression Pattern Description
Spatial Annotation:
EMAGE:3370Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
3370_wholemount_strong_3D_1.wlz
3370_wholemount_moderate_3D_1.wlz
3370_wholemount_weak_3D_1.wlz
3370_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:3370_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
head mesenchyme
detected detected
regionalExpression in presumptive frontal bone mesenchyme
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:2683473
Entity Detected:Msx2, homeobox, msh-like 2 ( MGI:97169)
Notes:The Msx2 probe used in this study by Ishii et al., 2003 [PMID:14597577] is described as the "entire first exon, [and] was amplified from a full-length mouse cDNA by PCR and cloned into the EcoRI and SalI sites of pBSKII(+)." Editor's Note: The exact start and end points of the probe are not specified by the authors.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:10.5 dpc
Theiler Stage:TS18
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Ishii M; Merrill AE; Chan YS; Gitelman I; Rice DP; Sucov HM; Maxson RE Jr, 2003 [PMID:14597577] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1242/dev.00793] [ PMID:14597577] Ishii M, Merrill AE, Chan YS, Gitelman I, Rice DP, Sucov HM, Maxson RE 2003 Msx2 and Twist cooperatively control the development of the neural crest-derived skeletogenic mesenchyme of the murine skull vault. Development (130):6131-42
Links:MGI:2683477 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI