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EMAGE:3371

Nefl neurofilament, light polypeptide ( MGI:97313)
TS17 (10.5 dpc)
in situ hybridisation

Data Images
EMAGE:3371
Figure 3G of White et al., 2003 [PMID:12620991] . Copyright: This image is from White et al., Development 130. 1681-1690 (2003), and is displayed with the permission of The Company of Biologists Limited who owns the Copyright.

Expression pattern clarity: two stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Note: Authors report that the designation "normal" is given to embryos that were either wild type or heterozygous Tbx6<tm1Pa>/Tbx6<+>.
Expression Pattern Description
Spatial Annotation:
EMAGE:3371Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
3371_wholemount_strong_3D_1.wlz
3371_wholemount_moderate_3D_1.wlz
3371_wholemount_possible_3D_1.wlz
3371_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:3371_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
neural tube
detected detected
tail neural tube
detected detected
spinal ganglion
detected detected
Expression in spinal ganglia as evenly distributed blocks along the axis, reflecting migration route through rostral halves of somites.
trunk somite
detected detected
regionalExpression in spinal ganglia as evenly distributed blocks along the axis, reflecting migration route through rostral halves of somites.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:2676961
Entity Detected:Nefl, neurofilament, light polypeptide ( MGI:97313)
Notes:The Nefl probe used in this study by White et al., 2003 [PMID:12620991] is of undefined sequence.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:10.5 dpc
Theiler Stage:TS17
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:White PH; Farkas DR; McFadden EE; Chapman DL, 2003 [PMID:12620991] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1242/dev.00367] [ PMID:12620991] White PH, Farkas DR, McFadden EE, Chapman DL 2003 Defective somite patterning in mouse embryos with reduced levels of Tbx6. Development (130):1681-90
Links:MGI:2676985 same experiment
 MGI:2447721 allele description
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI