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EMAGE:3375

Pax6 paired box gene 6 ( MGI:97490)
TS18 (10.5 dpc)
immunohistochemistry

Data Images
EMAGE:3375
Figure 1B of Toresson et al., 2000 [PMID:11003836] .Copyright: This image is from Toresson et al., Development 127:4361-4371 (2000), and is displayed with the permission of The Company of Biologists Limited who owns the Copyright.

Expression pattern clarity: two stars
Find spatially similar expression patterns: Find spatially similar patterns
Notes:
Note: Coronal section of telencephalon at E10.5. Arrow, ventral limit of PAX6 expression domain. MGE, medial ganglionic eminence.
Expression Pattern Description
Spatial Annotation:
EMAGE:3375EMAGE:3375Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
3D mappingspatial mapping

View mapped 3D expression image EMAGE genex expression entry
Download individual expression domains:
3375_voxel_strong_3D_1.wlz
3375_voxel_moderate_3D_1.wlz
3375_voxel_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:3375_all_domains.zip
Find spatially similar expression patterns: EMAGE spatially similar patterns
Morphological match to the template: one star
Text Annotation:
StructureLevelPatternNotes
telencephalon
detected detected
regionalIn ventral telencephalon, expressed in cortex; cells expressing high levels dorsal to domain of GSH2 expression in cortical ventricular zone (VZ).
Annotation Validation: EMAGE Editor
Detection Reagent
Type:antibody
Identifier:MGI:2150170
Entity Detected:Pax6, paired box gene 6 ( MGI:97490)
Notes:The anti-PAX6 antibody used in this study by Toresson et al., 2000 [PMID:11003836] is described as a "rabbit anti-PAX6 at 1:400 (provided by S. Wilson)".
Antibody Type:polyclonal
Raised In:rabbit
Specimen
Organism:mouse
Age:10.5 dpc
Theiler Stage:TS18
Mutations:none (wild-type)
Preparation:section
Procedures
Fixation:4% paraformaldehyde
Embedding:cryosection
General Information
Authors:Toresson H; Potter SS; Campbell K, 2000 [PMID:11003836] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:11003836] Toresson H, Potter SS, Campbell K 2000 Genetic control of dorsal-ventral identity in the telencephalon: opposing roles for Pax6 and Gsh2. Development (127):4361-71
Links:MGI:2150331 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI