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EMAGE:3402

Dlx5 distal-less homeobox 5 ( MGI:101926)
TS17 (10.5 dpc)
in situ hybridisation

Data Images
EMAGE:3402
Figure 1I of Depew et al., 1999 [PMID:10433912] . Copyright: This image is from Depew MJ, Development 1999;126():3831-46, and is displayed with the permission of The Company of Biologists Limited who owns the Copyright.

Expression pattern clarity: two stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Note: BA1=first branchial arch, BA2= second branchial arch, BA3= third branchial arch, BA4= fourth branchial arch, MdA= mandibular arch, MxA= maxillary arch, OfPt= olfactory pit, OV= otic vesicle.
Expression Pattern Description
Spatial Annotation:
EMAGE:3402Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
3402_wholemount_strong_3D_1.wlz
3402_wholemount_moderate_3D_1.wlz
3402_wholemount_possible_3D_1.wlz
3402_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:3402_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
otocyst
detected detected
regionalExpression is in the ectomesenchyme. The authors uses the term "otic pit".
1st branchial arch
detected detected
regionalExpression is in the ectomesenchyme.
2nd branchial arch
detected detected
regionalExpression is in the ectomesenchyme.
3rd branchial arch
detected detected
regionalExpression is in the ectomesenchyme.
4th branchial arch
detected detected
regionalExpression is in the ectomesenchyme.
frontal process ectoderm
detected detected
latero-nasal process ectoderm
detected detected
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:1339070
Entity Detected:Dlx5, distal-less homeobox 5 ( MGI:101926)
Notes:The Dlx5 probe used in this study by Depew et al., 1999 [PMID:10433912] was originally described in Qiu et al., 1997 [PMID:9187081] as "a 1-kb cDNA containing its homeobox and 3' sequences (Liu and Rubenstein, unpublished)." Editors note: exact start and end points of the probe sequence are undefined.
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Strain:C57BL/6J
Age:10.5 dpc
Theiler Stage:TS17
Mutations:none (wild-type)
Preparation:wholemount
Procedures
Fixation:4% paraformaldehyde
General Information
Authors:Depew MJ; Liu JK; Long JE; Presley R; Meneses JJ; Pedersen RA; Rubenstein JL, 1999 [PMID:10433912] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:10433912] Depew MJ, Liu JK, Long JE, Presley R, Meneses JJ, Pedersen RA, Rubenstein JL 1999 Dlx5 regulates regional development of the branchial arches and sensory capsules. Development (126):3831-46
 [ doi:10.1006/dbio.1997.8556] [ PMID:9187081] Qiu M, Bulfone A, Ghattas I, Meneses JJ, Christensen L, Sharpe PT, Presley R, Pedersen RA, Rubenstein JL 1997 Role of the Dlx homeobox genes in proximodistal patterning of the branchial arches: mutations of Dlx-1, Dlx-2, and Dlx-1 and -2 alter morphogenesis of proximal skeletal and soft tissue structures derived from the first and second arches. Dev Biol (185):165-84
Links:MGI:1342230 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI