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EMAGE:3403

Dlx5 distal-less homeobox 5 ( MGI:101926)
TS17 (10.5 dpc)
in situ hybridisation

Data Images
EMAGE:3403 EMAGE:3403
Figure 4E of Ruest et al., 2004 [PMID:15306564] . Copyright: This image is from Ruest LB, Development 2004 Sep;131(18):4413-23 and is displayed with the permission of The Company of Biologists Limited who owns the Copyright. Figure 4E of Ruest et al., 2004 [PMID:15306564] . Copyright: This image is from Ruest LB, Development 2004 Sep;131(18):4413-23 and is displayed with the permission of The Company of Biologists Limited who owns the Copyright.

Expression pattern clarity: two stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Abbreviations: 1= mandibular region of the first pharyngeal arch; 2= second pharyngeal arch; h= heart; lb= limb bud; np= nasal prominence.
Expression Pattern Description
Spatial Annotation:
EMAGE:3403Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
3403_wholemount_strong_3D_1.wlz
3403_wholemount_moderate_3D_1.wlz
3403_wholemount_weak_3D_1.wlz
3403_wholemount_possible_3D_1.wlz
3403_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:3403_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
1st branchial arch mandibular component
detected detected
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:1196065
Entity Detected:Dlx5, distal-less homeobox 5 ( MGI:101926)
Notes:The Dlx5 probe used in this assay by Ruest et al., 2004 [PMID:15306564] was originally described in Liu et al., 1997 [PMID:9415433] as an "RNA probe from a 1.3 kb cDNA clone". Editors note: MGI:1196065 gives a fuller description of the Dlx5 probe used in this assay, but the details could not be verified.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:10.5 dpc
Theiler Stage:TS17
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Ruest LB; Xiang X; Lim KC; Levi G; Clouthier DE, 2004 [PMID:15306564] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1242/dev.01291] [ PMID:15306564] Ruest LB, Xiang X, Lim KC, Levi G, Clouthier DE 2004 Endothelin-A receptor-dependent and -independent signaling pathways in establishing mandibular identity. Development (131):4413-23
 [ doi:10.1002/(SICI)1097-0177(199712)210:4<498::AID-AJA12>3.0.CO;2-3] [ PMID:9415433] Liu JK, Ghattas I, Liu S, Chen S, Rubenstein JL 1997 Dlx genes encode DNA-binding proteins that are expressed in an overlapping and sequential pattern during basal ganglia differentiation. Dev Dyn (210):498-512
Links:MGI:3510691 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI