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EMAGE:3425

Ednra endothelin receptor type A ( MGI:105923)
TS15 (9.5 dpc)
in situ hybridisation

Data Images
EMAGE:3425 EMAGE:3425
Figure 1C of Clouthier et al., 1998 [PMID:9449664] . Copyright: This image is from Clouthier et al., Development 125:813-824 (1998), and is displayed with the permission of The Company of Biologists Limited who owns the Copyright. Figure 1E of Clouthier et al., 1998 [PMID:9449664] . Copyright: This image is from Clouthier et al., Development 125:813-824 (1998), and is displayed with the permission of The Company of Biologists Limited who owns the Copyright.

Expression pattern clarity: two stars
Find spatially similar expression patterns: Find spatially similar patterns
Notes:
Note: Transverse sections. ov, otic vesicle; pa, pharyngeal arch; pp, pharyngeal pouch.
Expression Pattern Description
Spatial Annotation:
EMAGE:3425EMAGE:3425EMAGE:3425Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
3D mapping3D mappingspatial mapping

View mapped 3D expression image EMAGE genex expression entry
Download individual expression domains:
3425_voxel_moderate_3D_1.wlz
3425_voxel_weak_3D_1.wlz
3425_voxel_notDetected_3D_1.wlz
3425_voxel_strong_3D_1.wlz
3425_voxel_moderate_3D_2.wlz
3425_voxel_notDetected_3D_2.wlz
3425_voxel_strong_3D_2.wlz
3425_voxel_weak_3D_2.wlz
(what is wlz format?)
Download all expression domains: EMAGE:3425_all_domains.zip
Find spatially similar expression patterns: EMAGE spatially similar patterns
Morphological match to the template: one star
Text Annotation:
StructureLevelPatternNotes
head mesenchyme derived from neural crest
detected detected
trunk mesenchyme
detected detected
1st branchial arch mandibular component mesenchyme derived from neural crest
detected detected
The arch epithelium was negative.
1st branchial arch maxillary component mesenchyme derived from neural crest
detected detected
The arch epithelium was negative.
2nd branchial arch mesenchyme derived from neural crest
detected detected
regionalExpression in the 2nd arch mesenchyme is less abundant in the core. The arch epithelium was negative.
3rd branchial arch mesenchyme derived from neural crest
detected detected
The arch epithelium was negative.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:1261446
Entity Detected:Ednra, endothelin receptor type A ( MGI:105923)
Notes:The Ednra (ETa) probe used in this study by Clouthier et al., 1998 [PMID:9449664] was described as "a 350 bp BamHI-EcoRI fragment", "from a mouse cDNA". Editor's note: Restriction digestion of the Ednra RefSeq mouse cDNA (NM_010332.2.) with BamHI and EcoRI does not identify a 350bp fragment. It identifies a 490bp EcoRI-BamHI fragment. Ambiguous information.
Chemistry:RNA
Strand:antisense
Label:S35
Specimen
Organism:mouse
Strain:129S/SvEv
Age:9.5 dpc
Theiler Stage:TS15
Mutations:none (wild-type)
Preparation:section
Procedures
Fixation:4% paraformaldehyde
Staining procedure:autoradiography
General Information
Authors:Clouthier DE; Hosoda K; Richardson JA; Williams SC; Yanagisawa H; Kuwaki T; Kumada M; Hammer RE; Yanagisawa M, 1998 [PMID:9449664] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:9449664] Clouthier DE, Hosoda K, Richardson JA, Williams SC, Yanagisawa H, Kuwaki T, Kumada M, Hammer RE, Yanagisawa M 1998 Cranial and cardiac neural crest defects in endothelin-A receptor-deficient mice. Development (125):813-24
Links:MGI:1290061 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI