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EMAGE:3427

Ednra endothelin receptor type A ( MGI:105923)
TS15 (9.5 dpc)
in situ hybridisation

Data Images
EMAGE:3427
Figure 7E of Clouthier et al., 1998 [PMID:9449664] . Copyright: This image is from Clouthier et al., Development 125:813-824 (1998), and is displayed with the permission of The Company of Biologists Limited who owns the Copyright.

Expression pattern clarity: two stars
Find spatially similar expression patterns: Find spatially similar patterns
Notes:
Note: Sagittal section. arrow, encocardial layer. A, atrium; BC, bulbus cordis; pa1, pharyngeal arch 1; TA, truncus arteriosus.
Expression Pattern Description
Spatial Annotation:
EMAGE:3427EMAGE:3427Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
3D mappingspatial mapping

View mapped 3D expression image EMAGE genex expression entry
Download individual expression domains:
3427_voxel_strong_3D_1.wlz
3427_voxel_moderate_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:3427_all_domains.zip
Find spatially similar expression patterns: EMAGE spatially similar patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
common atrial chamber cardiac muscle
strong strong
bulbus cordis
strong strong
primitive ventricle cardiac muscle
detected detected
arterial system
strong strong
regionalAbundant expression was also found in the mesenchyme of the aortic arch.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:1261446
Entity Detected:Ednra, endothelin receptor type A ( MGI:105923)
Notes:The Ednra (ETa) probe used in this study by Clouthier et al., 1998 [PMID:9449664] was described as "a 350 bp BamHI-EcoRI fragment", "from a mouse cDNA". Editor's note: Restriction digestion of the Ednra RefSeq mouse cDNA (NM_010332.2.) with BamHI and EcoRI does not identify a 350bp fragment. It identifies a 490bp EcoRI-BamHI fragment. Ambiguous information.
Chemistry:RNA
Strand:antisense
Label:S35
Specimen
Organism:mouse
Strain:129S/SvEv
Age:9.5 dpc
Theiler Stage:TS15
Mutations:none (wild-type)
Preparation:section
Procedures
Fixation:4% paraformaldehyde
Staining procedure:autoradiography
General Information
Authors:Clouthier DE; Hosoda K; Richardson JA; Williams SC; Yanagisawa H; Kuwaki T; Kumada M; Hammer RE; Yanagisawa M, 1998 [PMID:9449664] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:9449664] Clouthier DE, Hosoda K, Richardson JA, Williams SC, Yanagisawa H, Kuwaki T, Kumada M, Hammer RE, Yanagisawa M 1998 Cranial and cardiac neural crest defects in endothelin-A receptor-deficient mice. Development (125):813-24
Links:MGI:1290061 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI