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EMAGE:3489

Otx2 orthodenticle homolog 2 (Drosophila) ( MGI:97451)
TS09 (6.7 dpc)
in situ hybridisation

Data Images
EMAGE:3489 EMAGE:3489
Fig1D.Copyright: Reprinted with permission from Elsevier from [doi:10.1016/S1567-133X(03)00056-5] Gene Expr Patterns 3: 497-501, Acampora D; Annino A; Puelles E; Alfano I; Tuorto F; Simeone A, OTX1 compensates for OTX2 requirement in regionalisation of anterior neuroectoderm. Copyright 2003 Fig1E.Copyright: Reprinted with permission from Elsevier from [doi:10.1016/S1567-133X(03)00056-5] Gene Expr Patterns 3: 497-501, Acampora D; Annino A; Puelles E; Alfano I; Tuorto F; Simeone A, OTX1 compensates for OTX2 requirement in regionalisation of anterior neuroectoderm. Copyright 2003

Expression pattern clarity: one star
Find spatially similar expression patterns: Find spatially similar patterns
Notes:
Image annotations: Ec - primitive ectoderm; ps - primitive streak; AVE - anterior visceral endoderm. NOTE: Image E is an adjacent section immunostained with the anti-OTX2 antibody, and is included here to show embryo morphology.
Expression Pattern Description
Spatial Annotation:
EMAGE:3489EMAGE:3489Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
3D mappingspatial mapping

View mapped 3D expression image EMAGE genex expression entry
Download individual expression domains:
3489_voxel_strong_3D_1.wlz
3489_voxel_moderate_3D_1.wlz
3489_voxel_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:3489_all_domains.zip
Find spatially similar expression patterns: EMAGE spatially similar patterns
Morphological match to the template: one star
Text Annotation:
StructureLevelPatternNotes
primitive endoderm
detected detected
Expression in Anterior Visceral Endoderm
embryo ectoderm
detected detected
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:3045220
Entity Detected:Otx2, orthodenticle homolog 2 (Drosophila) ( MGI:97451)
Notes:The Otx2 probe used in this study by Acampora et al., 2003 [PMID:12915318] is shown schematically as a hatched box marked "a" in figure 1A of the paper. It covers the 5' part of exon 3, but its exact sequence (start and end points) are not defined.
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Age:6.7 dpc
Theiler Stage:TS09
Mutations:none (wild-type)
Preparation:section
Procedures
General Information
Authors:Acampora D; Annino A; Puelles E; Alfano I; Tuorto F; Simeone A, 2003 [PMID:12915318] , Indexed by GXD, Spatially Mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1016/S1567-133X(03)00056-5] [ PMID:12915318] Acampora D, Annino A, Puelles E, Alfano I, Tuorto F, Simeone A 2003 OTX1 compensates for OTX2 requirement in regionalisation of anterior neuroectoderm. Gene Expr Patterns (3):497-501
Links:MGI:3045223 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI