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EMAGE:3564

Dlx3 distal-less homeobox 3 ( MGI:94903)
TS17 (10.5 dpc)
in situ hybridisation

Data Images
EMAGE:3564 EMAGE:3564
Fig 8CCopyright: Reprinted with permission from Elsevier from [doi:10.1006/dbio.1997.8556] Dev Biol 185: 165-84, Qiu M; Bulfone A; Ghattas I; Meneses JJ; Christensen L; Sharpe PT; Presley R; Pedersen RA; Rubenstein JL, Role of the Dlx homeobox genes in proximodistal patterning of the branchial arches: mutations of Dlx-1, Dlx-2, and Dlx-1 and -2 alter morphogenesis of proximal skeletal and soft tissue structures derived from the first and second arches. Copyright 1997 Fig 8DCopyright: Reprinted with permission from Elsevier from [doi:10.1006/dbio.1997.8556] Dev Biol 185: 165-84, Qiu M; Bulfone A; Ghattas I; Meneses JJ; Christensen L; Sharpe PT; Presley R; Pedersen RA; Rubenstein JL, Role of the Dlx homeobox genes in proximodistal patterning of the branchial arches: mutations of Dlx-1, Dlx-2, and Dlx-1 and -2 alter morphogenesis of proximal skeletal and soft tissue structures derived from the first and second arches. Copyright 1997

Expression pattern clarity: two stars
Find spatially similar expression patterns: Find spatially similar patterns
Notes:
Image annotations: Arrow - ectodermal expression of Dlx-3 in the medial mandibular arch; Md - mandibular branch of first branchial arch.
Expression Pattern Description
Spatial Annotation:
EMAGE:3564EMAGE:3564EMAGE:3564Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
3D mapping3D mappingspatial mapping

View mapped 3D expression image EMAGE genex expression entry
Download individual expression domains:
3564_voxel_moderate_3D_1.wlz
3564_voxel_notDetected_3D_1.wlz
3564_voxel_strong_3D_1.wlz
3564_voxel_possible_3D_1.wlz
3564_voxel_moderate_3D_2.wlz
3564_voxel_notDetected_3D_2.wlz
3564_voxel_strong_3D_2.wlz
(what is wlz format?)
Download all expression domains: EMAGE:3564_all_domains.zip
Find spatially similar expression patterns: EMAGE spatially similar patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
1st branchial arch
detected detected
regionalDlx-3 expression is restricted to more distal domains. The Dlx genes also have a graded expression along the mediolateral axis of the arches.
2nd branchial arch
detected detected
regional
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:25894
Entity Detected:Dlx3, distal-less homeobox 3 ( MGI:94903)
Notes:The Dlx3 probe used in this study by Qiu et al., 1997 [PMID:9187081] is described as being obtained from K. Mahon (Robinson & Mahon, 1994, [PMID:7893603] ), where it is described as containing a 1.1-kb cDNA insert. Editors note: probe end points are not defined.
Chemistry:RNA
Strand:antisense
Label:unspecified radioactivity
Specimen
Organism:mouse
Age:10.5 dpc
Theiler Stage:TS17
Mutations:none (wild-type)
Preparation:section
Procedures
Staining procedure:autoradiography
General Information
Authors:Qiu M; Bulfone A; Ghattas I; Meneses JJ; Christensen L; Sharpe PT; Presley R; Pedersen RA; Rubenstein JL, 1997 [PMID:9187081] , Indexed by GXD, Spatially Mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1006/dbio.1997.8556] [ PMID:9187081] Qiu M, Bulfone A, Ghattas I, Meneses JJ, Christensen L, Sharpe PT, Presley R, Pedersen RA, Rubenstein JL 1997 Role of the Dlx homeobox genes in proximodistal patterning of the branchial arches: mutations of Dlx-1, Dlx-2, and Dlx-1 and -2 alter morphogenesis of proximal skeletal and soft tissue structures derived from the first and second arches. Dev Biol (185):165-84
 [ doi:10.1016/0925-4773(94)90060-4] [ PMID:7893603] Robinson GW, Mahon KA 1994 Differential and overlapping expression domains of Dlx-2 and Dlx-3 suggest distinct roles for Distal-less homeobox genes in craniofacial development. Mech Dev (48):199-215
Links:MGI:1339101 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI