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EMAGE:3566

Dlx3 distal-less homeobox 3 ( MGI:94903)
TS15 (9.5 dpc)
in situ hybridisation

Data Images
EMAGE:3566 EMAGE:3566
Fig 2CCopyright: Reprinted with permission from Elsevier from [doi:10.1006/dbio.1999.9527] Dev Biol 217: 10-24, Clouthier DE; Williams SC; Yanagisawa H; Wieduwilt M; Richardson JA; Yanagisawa M, Signaling pathways crucial for craniofacial development revealed by endothelin-A receptor-deficient mice. Copyright 2000 Fig 2DCopyright: Reprinted with permission from Elsevier from [doi:10.1006/dbio.1999.9527] Dev Biol 217: 10-24, Clouthier DE; Williams SC; Yanagisawa H; Wieduwilt M; Richardson JA; Yanagisawa M, Signaling pathways crucial for craniofacial development revealed by endothelin-A receptor-deficient mice. Copyright 2000

Expression pattern clarity: two stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image annotations: The pharyngeal arches (1 and 2) are outlined; h - heart; arrows indicate mesenchyme of arches; arrow indicates epithelium of arches.
Expression Pattern Description
Spatial Annotation:
EMAGE:3566Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
3566_wholemount_strong_3D_1.wlz
3566_wholemount_possible_3D_1.wlz
3566_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:3566_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
1st branchial arch mandibular component ectoderm
detected detected
1st branchial arch mandibular component mesenchyme
detected detected
2nd branchial arch ectoderm
detected detected
2nd branchial arch mesenchyme
detected detected
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:25894
Entity Detected:Dlx3, distal-less homeobox 3 ( MGI:94903)
Notes:The Dlx3 probe used in this study by Clouthier et al, 2000 [PMID:10625532] is described as being thatused by Robinson & Mahon, 1994, [PMID:7893603] , where it is described as containing a 1.1-kb cDNA insert.
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Age:9.5 dpc
Theiler Stage:TS15
Mutations:none (wild-type)
Preparation:wholemount
Procedures
Fixation:4% paraformaldehyde
General Information
Authors:Clouthier DE; Williams SC; Yanagisawa H; Wieduwilt M; Richardson JA; Yanagisawa M, 2000 [PMID:10625532] , Indexed by GXD, Spatially Mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1006/dbio.1999.9527] [ PMID:10625532] Clouthier DE, Williams SC, Yanagisawa H, Wieduwilt M, Richardson JA, Yanagisawa M 2000 Signaling pathways crucial for craniofacial development revealed by endothelin-A receptor-deficient mice. Dev Biol (217):10-24
 [ doi:10.1016/0925-4773(94)90060-4] [ PMID:7893603] Robinson GW, Mahon KA 1994 Differential and overlapping expression domains of Dlx-2 and Dlx-3 suggest distinct roles for Distal-less homeobox genes in craniofacial development. Mech Dev (48):199-215
Links:MGI:2135643 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI