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EMAGE:3567

Dlx3 distal-less homeobox 3 ( MGI:94903)
TS18 (10.5 dpc)
in situ hybridisation

Data Images
EMAGE:3567 EMAGE:3567
Fig2GCopyright: Reprinted with permission from Elsevier from [doi:10.1006/dbio.1999.9527] Dev Biol 217: 10-24, Clouthier DE; Williams SC; Yanagisawa H; Wieduwilt M; Richardson JA; Yanagisawa M, Signaling pathways crucial for craniofacial development revealed by endothelin-A receptor-deficient mice. Copyright 2000 Fig 2HCopyright: Reprinted with permission from Elsevier from [doi:10.1006/dbio.1999.9527] Dev Biol 217: 10-24, Clouthier DE; Williams SC; Yanagisawa H; Wieduwilt M; Richardson JA; Yanagisawa M, Signaling pathways crucial for craniofacial development revealed by endothelin-A receptor-deficient mice. Copyright 2000

Expression pattern clarity: two stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image annotations: Figure H is a frontal view (with the heart removed) of the embryo shown in Figure G. The pharyngeal arches (1 & 2) are outlined; h- heart; arrowheads - nasal process epithelium.
Expression Pattern Description
Spatial Annotation:
EMAGE:3567Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
3567_wholemount_strong_3D_1.wlz
3567_wholemount_moderate_3D_1.wlz
3567_wholemount_possible_3D_1.wlz
3567_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:3567_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
1st branchial arch
detected detected
regionalExpression is in the posterior half.
2nd branchial arch
detected detected
nasal process
detected detected
regionalExpression is in the epithelium.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:25894
Entity Detected:Dlx3, distal-less homeobox 3 ( MGI:94903)
Notes:The Dlx3 probe used in this study by Clouthier et al, 2000 [PMID:10625532] is described as being that used by Robinson & Mahon, 1994, [PMID:7893603] , where it is described as containing a 1.1-kb cDNA insert.
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Age:10.5 dpc
Theiler Stage:TS18
Mutations:none (wild-type)
Preparation:wholemount
Procedures
Fixation:4% paraformaldehyde
General Information
Authors:Clouthier DE; Williams SC; Yanagisawa H; Wieduwilt M; Richardson JA; Yanagisawa M, 2000 [PMID:10625532] , Indexed by GXD, Spatially Mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1006/dbio.1999.9527] [ PMID:10625532] Clouthier DE, Williams SC, Yanagisawa H, Wieduwilt M, Richardson JA, Yanagisawa M 2000 Signaling pathways crucial for craniofacial development revealed by endothelin-A receptor-deficient mice. Dev Biol (217):10-24
 [ doi:10.1016/0925-4773(94)90060-4] [ PMID:7893603] Robinson GW, Mahon KA 1994 Differential and overlapping expression domains of Dlx-2 and Dlx-3 suggest distinct roles for Distal-less homeobox genes in craniofacial development. Mech Dev (48):199-215
Links:MGI:2135643 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI