EMAGE mouse gene expression spatial database

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EMAGE:3600

Efna1 ephrin A1 ( MGI:103236)
TS12 (8.5 dpc)
in situ hybridisation

Data Images


Fig1G.Copyright: Reprinted with permission from Elsevier from [doi:10.1016/S0925-4773(98)00142-7] Mech Dev 77: 201-4, McBride JL; Ruiz JC, Ephrin-A1 is expressed at sites of vascular development in the mouse. Copyright 1998	Fig1E.Copyright: Reprinted with permission from Elsevier from [doi:10.1016/S0925-4773(98)00142-7] Mech Dev 77: 201-4, McBride JL; Ruiz JC, Ephrin-A1 is expressed at sites of vascular development in the mouse. Copyright 1998	Fig1F.Copyright: Reprinted with permission from Elsevier from [doi:10.1016/S0925-4773(98)00142-7] Mech Dev 77: 201-4, McBride JL; Ruiz JC, Ephrin-A1 is expressed at sites of vascular development in the mouse. Copyright 1998	Fig1H.Copyright: Reprinted with permission from Elsevier from [doi:10.1016/S0925-4773(98)00142-7] Mech Dev 77: 201-4, McBride JL; Ruiz JC, Ephrin-A1 is expressed at sites of vascular development in the mouse. Copyright 1998

Expression pattern clarity:
Find spatially similar expression patterns:

Notes:

Transverse sections of an 8.5 dpc embryo through the trunk region (F), midbrain/heart (G), and caudal neuropore and allantois (H) Image annotations: a, allantois; b, bulbus cordis; da, dorsal aorta; e, endocardium; en, anterior pharyngeal endoderm; pv, primary head vein; v, ventricle. Bar=50 microns. Of the 4 data images, only sections F and G were spatially annotated in this EMAGE entry.

Expression Pattern Description

Spatial Annotation:

Annotation colour key:

	strong
	moderate
	weak
	possible
	not detected

3D mapping

spatial mapping

View mapped 3D expression image

Download individual expression domains:

3600_voxel_notDetected_3D_1.wlz

3600_voxel_strong_3D_1.wlz

3600_voxel_notDetected_3D_2.wlz

3600_voxel_strong_3D_2.wlz

(what is wlz format?)

Download all expression domains:

EMAGE:3600_all_domains.zip

Find spatially similar expression patterns:

Morphological match to the template:

Text Annotation:

Structure

Level

Pattern

Notes

dorsal aorta

detected

bulbus cordis rostral half endocardial tube

detected

outflow tract endocardial tube

detected

primitive ventricle endocardial tube

detected

primary head vein

detected

allantois

detected

regional

Expression is in the allantoic vessel.

Annotation Validation:

EMAGE Editor

Detection Reagent

Type:	in situ hybridisation probe
Identifier:	MGI:2445336
Entity Detected:	Efna1, ephrin A1 ( MGI:103236)
Notes:	The template clone used to make the Efna1 probe used in this study by McBride & Ruiz, 1998 [PMID:9831653] is described as a "1.3 kb mouse B61 cDNA clone" that was obtained from Dr. R. Lindberg (AMGEN, Inc.). Editors Note: the actual start and end points of the probe sequence are not reported.
Chemistry:	RNA
Strand:	antisense
Label:	digoxigenin

Specimen

Organism:	mouse
Age:	8.5 dpc
Theiler Stage:	TS12
Mutations:	none (wild-type)
Preparation:	sectioned wholemount

Procedures

Fixation:

4% paraformaldehyde

General Information

Authors:	McBride JL; Ruiz JC (1998) [PMID:9831653] . Indexed by GXD, Spatially mapped by EMAGE
Submitted by:	EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:	non-screen
References:	[ doi:10.1016/S0925-4773(98)00142-7] [ PMID:9831653] McBride JL, Ruiz JC 1998 Ephrin-A1 is expressed at sites of vascular development in the mouse. Mech Dev (77):201-4
Links:	MGI:2446521 same experiment
	Ensembl same gene
	Allen Brain Atlas same gene
	BioGPS same gene
	International Mouse Knockout Project Status same gene
	GEISHA Chicken ISH Database same gene
	EMBL-EBI Gene Expression Atlas same gene
	BrainStars same gene
	ViBrism same gene
Data Source