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EMAGE:3607

Alx1 ALX homeobox 1 ( MGI:104621)
TS15 (9.5 dpc)
in situ hybridisation

Data Images
EMAGE:3607 EMAGE:3607
Fig2C.Copyright: Reprinted with permission from Elsevier from [doi:10.1016/S0925-4773(01)00450-6] Mech Dev 107: 163-7, Beverdam A; Meijlink F, Expression patterns of group-I aristaless-related genes during craniofacial and limb development. Copyright 2001 Fig1I.Copyright: Reprinted with permission from Elsevier from [doi:10.1016/S0925-4773(01)00450-6] Mech Dev 107: 163-7, Beverdam A; Meijlink F, Expression patterns of group-I aristaless-related genes during craniofacial and limb development. Copyright 2001

Expression pattern clarity: three stars
Find spatially similar expression patterns: Find spatially similar patterns
Notes:
The section in 2C is transverse. Fig 1I is included to show a wholemount ISH for Cart1 of a similarly aged embryo to the sectioned embryo. The arrow points to expression in the mesenchyme underlying the nasal placode.
Expression Pattern Description
Spatial Annotation:
EMAGE:3607EMAGE:3607Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
3D mappingspatial mapping

View mapped 3D expression image EMAGE genex expression entry
Download individual expression domains:
3607_voxel_strong_3D_1.wlz
3607_voxel_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:3607_all_domains.zip
Find spatially similar expression patterns: EMAGE spatially similar patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
fronto-nasal process mesenchyme
strong strong
regionalExpression is in the mesenchyme underlying the nasal placodes
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:889863
Entity Detected:Alx1, ALX homeobox 1 ( MGI:104621)
Sequence:sense strand is shown

>MGI:889863
CTATCCTTGGGGACAAATGTGACAGCAATGTATCCAGCAGCAAAAAGAGGAGACACCGAACTACCTTTAC
CAGTTTGCAGCTGGAGGAACTGGAGAAAGTTTTCCAGAAAACCCATTACCCAGATGTATATGTCAGAGAA
CAACTTGCCCTGAGAACGGAGCTCACTGAGGCCAGGGTCCAGGTTTGGTTTCAAAATCGAAGGGCCAAGT
GGAGAAAAAGAGAACGATACGGCCAAATACAGCAAGCTAAAAGCCATTTCGCTGCCACGTACGACATATC
AGCCTTACCAAGGACGGACAGCTACCCACAGATCCAGAACAATTTGTGGGCAGGAAATGCTAGCGGTGGT
TCTGTGGTTACGTCATGCATGCTACCACGTGACGCGTCCTCCTGCATGACACCTTACTCTCACTCGCCTC
GGACAGATTCCAGTTATACGGGGTTTTCGAACCACCAGAATCAGTTCAGCCACGTGCCCCTCAATAATTT
TTTCACTGACTCTCTTCTCACTGGAGCTACCAACGGACACGCATTTGAAACAAAGCCGGAGTTTGAAAGG
AGGTCT
Notes:The Cart1 probe used in this study by Beverdam & Meijlink, 2001 [PMID:11520673] is indicated as that used by tenBerge et al, 1998 [PMID:9676189] . tenBerge et al describe the template clone as thus: "Based on its sequence present in the EMBL/Genbank database, an EST clone (Accession No. AA388194) represents a mouse Cart1 cDNA. We purchased this cDNA, cloned in the vector pSport1, from Genome Systems (St. Louis, MO; clone ID 790077) and reconfirmed by sequencing its extreme high similarity at the level of the inferred translation product (65 identical amino acids in a stretch of 66, in comparison to human Cart1". Editor's note: the only publicly available insert sequence of this clone is the short EST read AA388194.1.
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Age:9.5 dpc
Theiler Stage:TS15
Mutations:none (wild-type)
Preparation:section
Procedures
General Information
Authors:Beverdam A; Meijlink F (2001) [PMID:11520673] . Indexed by GXD, Spatially mapped by EMAGE
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1016/S0925-4773(01)00450-6] [ PMID:11520673] Beverdam A, Meijlink F 2001 Expression patterns of group-I aristaless-related genes during craniofacial and limb development. Mech Dev (107):163-7
 [ doi:10.1006/dbio.1998.8921] [ PMID:9676189] ten Berge D, Brouwer A, el Bahi S, Guénet JL, Robert B, Meijlink F 1998 Mouse Alx3: an aristaless-like homeobox gene expressed during embryogenesis in ectomesenchyme and lateral plate mesoderm. Dev Biol (199):11-25
Links:MGI:3039372 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI