EMAGE mouse gene expression spatial database

Quicksearch Help

(Click the icon to keep this page displayed.)

EMAGE:3633

Dlx1 distal-less homeobox 1 ( MGI:94901)
TS17 (10.5 dpc)
in situ hybridisation

Data Images


Fig 7ACopyright: Reprinted with permission from Elsevier from [doi:10.1006/dbio.1997.8556] Dev Biol 185: 165-84, Qiu M; Bulfone A; Ghattas I; Meneses JJ; Christensen L; Sharpe PT; Presley R; Pedersen RA; Rubenstein JL, Role of the Dlx homeobox genes in proximodistal patterning of the branchial arches: mutations of Dlx-1, Dlx-2, and Dlx-1 and -2 alter morphogenesis of proximal skeletal and soft tissue structures derived from the first and second arches. Copyright 1997	Fig 7BCopyright: Reprinted with permission from Elsevier from [ [doi:10.1006/dbio.1997.8556] Dev Biol 185: 165-84, Qiu M; Bulfone A; Ghattas I; Meneses JJ; Christensen L; Sharpe PT; Presley R; Pedersen RA; Rubenstein JL, Role of the Dlx homeobox genes in proximodistal patterning of the branchial arches: mutations of Dlx-1, Dlx-2, and Dlx-1 and -2 alter morphogenesis of proximal skeletal and soft tissue structures derived from the first and second arches. Copyright 1997

Expression pattern clarity:
Find spatially similar expression patterns:

Notes:

Image annotation: H - hyoid (second) branchial arch; Hb - hindbrain; Md - mandibular branch of first branchial arch; Np - nasal prominence; Of - olfactory pit; III - third ventricle. Both sections depict Dlx1 expression, however only the data from Fig7A was spatially annotated in this EMAGE entry.

Expression Pattern Description

Spatial Annotation:

Annotation colour key:

	strong
	moderate
	weak
	possible
	not detected

3D mapping

spatial mapping

View mapped 3D expression image

Download individual expression domains:

3633_voxel_strong_3D_1.wlz

3633_voxel_notDetected_3D_1.wlz

(what is wlz format?)

Download all expression domains:

EMAGE:3633_all_domains.zip

Find spatially similar expression patterns:

Morphological match to the template:

Text Annotation:

Structure

Level

Pattern

Notes

1st branchial arch

detected

regional

Dlx-1 is expressed in both proximal and distal regions of the first and second arches. The Dlx genes also have a graded expression along the mediolateral axis of the arches.

2nd branchial arch

detected

regional

Dlx-1 is expressed in both proximal and distal regions of the first and second arches. The Dlx genes also have a graded expression along the mediolateral axis of the arches.

Annotation Validation:

EMAGE Editor

Detection Reagent

Type:	in situ hybridisation probe
Identifier:	MGI:32409
Entity Detected:	Dlx1, distal-less homeobox 1 ( MGI:94901)
Sequence:	sense strand is shown >MGI:32409 CAGGCGTTGGGGGCGGGCGAAGGGTGGGGACAGCAAGGGGGAGGGCGACGGCAGGGCGCGGCTGGTTGGT TTCTGGGGCGGGAAGCGCGCGAGGGAGGCGGGAGGCTGGAGTCGCGCGCCTTCGAGGTTCCTGCGCGGAC GCCGCAGCCCATTGTGCGTCCCGCTCCGCGCGCTCTGTTGCAGAGGAGCCCCGGCCGGGACGTGTGGACC GGATTCTCCCCAGGCCGGGCCGCGTCGCCCGCTCTAGTCCAGCCGAGCCCGAGCTTCTCGGACCAATCCC CGGTGATTATGCAAGAGAGCCGACCAATCAGCTCCACCAGCTCATGAATATTTATGACCTTGGCTGAGTC AAAGCTTTGAACCGAGTTTGGGGAGCTCGGCAGCATCATGCTTAGACTTTTCAAAGAGACAAACTCCATT TTCTTATGAATGGAAAGTGAAAACCCCTGTTCCGCTTAAATTGGGTTCCTTCCTGTCCTGAGAAACATAG AGACCCCCAAAAGGGAAGCAGAGGAGAGAAAGACCCACACCCAGACCCCGCGAGAAGAGATGACCATGAC CACCATGCCAGAAAGTCTCAACAGCCCCGTGTCGGGCAAGGCTGTGTTTATGGAGTTTGGGCCGCCCAAC CAGCAAATGTCTCCTTCTCCCATGTCCCACGGGCACTACTCCATGCACTGTTTACACTCGGCGGGCCATT CGCAGCCCGACGGTGCCTACAGTTCGGCCTCATCCTTCTCCCGACCGCTGGGCTACCCCTACGTCAACTC GGTCAGCAGCCACGCGTCCAGCCCCTACATCAGTTCCGTGCAGTCCTACCCCGGCAGCGCCAGCCTCGCC CAGAGCCGCCTGGAGGACCCAGGGGCGGACTCCGAGAAGAGTACGGTGGTGGAAGGCGGCGAGGTGCGCT TTAACGGCAAAGGGAAAAAGATCCGTAAACCCAGGACAATTTATTCCAGTTTGCAGTTGCAGGCTTTGAA CCGGAGGTTCCAACAAACTCAGTACTTAGCTCTGCCTGAGAGGGCGGAGCTGGCGGCCTCCTTGGGACTC ACACAGACGCAGGTCAAGATATGGTTCCAGAACAAACGCTCCAAGTTCAAGAAGCTGATGAAGCAAGGCG GGGCAGCTCTGGAGGGCAGCGCGCTGGCGAACGGCAGAGCCTTGTCTGCCGGCTCCCCACCGGTACCACC CGGCTGGAATCCGAACTCCTCATCTGGGAAGGGCTCCGGCAGCAGCGCTGGCTCCTACGTCCCCAGCTAT ACATCATGGTATCCCTCAGCGCACCAAGAAGCTATGCAGCAGCCTCAACTGATGTGAGGTTATCAGTTCG CACTCACCCGCTTCCTGCCCGTCTCCCTTGGCCCGGCCCCTCCCGCCTCCAGGTTCATCCACCTTTTCGC ACGCCCTGGGCCAGGAGGAGAAGAGCCCACGAGCGGGAGCAGGGGTGGGGGTGGGGAGCTAAAAATAAAA GAAAAAGGAACAGTGAAGGCAGAGGGCTTGCTGCTTCTCGGAGCCCCTAAAAGTCTGACTCAGCGACCTT TCAGCCCGAATCTGGTTTGGGCCACGGTGAACAGCAGAGTGGCCTCAAAGCGCAGGCACAGCCACTGGAG ACAGCCAGTGCCACAAGATAACCCGCTGGACCGGACCAGACTCTCATCTTTGTGAGACTATCAGGAAAAA CAAATACGTAGGAGGGGGAAATACGCTCTTTTTTGATTCTGTCCGTCTTTGTCTCCTTTTTGCACTGTCT GTGCGCCGAAGTCAAGGTCCTCGTGTGTCTGCTGTCCTCATTCTACGACCTCTCCAAAAAGTCACCAGGT CTGAGCCACACCGGTCTGCCGGCAGCCCATCCACCGAGTCCTGGACCACTTTTTCCTGAATGGTCTTCTT CCGGGCCCTGCTTGACCATCTATGTAGCTTGTTTGGGAAATGGGGGAAATCAGAGGGAGGGGGGTTAATT TATTGAAAAACAGACTTCATCTGACGCTGAGTGTTGGCCAATTCCAAATTCTCTGGGACATGGAGTGGGC GCTGTCCAAACATACTATTTACCTTAAACACACCAGAAGAGGGAACAAGGACAGGAAAGTGACTTTTAAG GTGCACAGTAACTTTTGTACTTGGCTGAAATGCAGAAAGGGAAAACAGGATGCCGTGCATTTTACATGCT CCAAATTATTAAAAATAACAACAAAAGAAAGACCGAAGTAAGGAAGTAAGATATGTAAAACCAATAGGAT GTTGTCAAAAACGTTTGGACAAGAACACCTGGCCAAGAAGAAAAATCATACTTTGGGCAGCAAGAGAGAG GACCAATGAGCCTTGGAGAGAAAATAATTTGTCCTTTATGTAAAAGCACCCCAATTCCAGGTCGCTTTAA AGTAAGACACAAGCAGCGGCTCGACCACAGAACACAAGTCATCACCCTGAATGCACGGGCTCTGGTGCAA GATCTAATTGCTGTACATATTATTGTTGTTATTATTATTAATTATTATTATTATTGTTCTGTAAACATGT TGCACAAGCTTAGCCTCTTTCCGTTCTGTTGTGTGTGGCTGTAAACCCGATGCTTTGTGAAATGAGAATC TTGACATTTTACTTGTGAAATTTGGAAAATGTGACCGATTGAAATCCACCGTGTTTTGTGTTCTCTATGT CAAAGTTTAGTTTTATATTGAGAATGTTAACTTATTGCTTTGTATCTTGGGGGGGGGGCGAACTTTGTAA ATAAGTTATAAAGTTTCTTTGAGACAGTAAAATTATGGTTTCAAGAAAG
	nt 1 - nt 2779 of U51001.1
Notes:	The Dlx1 probe used in this study by Qiu et al., 1997 [PMID:9187081] was described as "generated from a full-length (2.8-kb) Dlx-1 cDNA clone (McGuinness et al., 1996 [PMID:8812481] ." Editors Note: U51001.1 is the sequence submitted to GenBank to accompany the McGuinness et al., 1996 publication.
Chemistry:	RNA
Strand:	antisense
Label:	unspecified radioactivity

Specimen

Organism:	mouse
Age:	10.5 dpc
Theiler Stage:	TS17
Mutations:	none (wild-type)
Preparation:	section

Procedures

Staining procedure:

autoradiography

General Information

Authors:	Qiu M; Bulfone A; Ghattas I; Meneses JJ; Christensen L; Sharpe PT; Presley R; Pedersen RA; Rubenstein JL, 1997 [PMID:9187081] , Indexed by GXD, Spatially Mapped by EMAGE.
Submitted by:	EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:	non-screen
References:	[ doi:10.1006/dbio.1997.8556] [ PMID:9187081] Qiu M, Bulfone A, Ghattas I, Meneses JJ, Christensen L, Sharpe PT, Presley R, Pedersen RA, Rubenstein JL 1997 Role of the Dlx homeobox genes in proximodistal patterning of the branchial arches: mutations of Dlx-1, Dlx-2, and Dlx-1 and -2 alter morphogenesis of proximal skeletal and soft tissue structures derived from the first and second arches. Dev Biol (185):165-84
	[ doi:10.1006/geno.1996.0387] [ PMID:8812481] McGuinness T, Porteus MH, Smiga S, Bulfone A, Kingsley C, Qiu M, Liu JK, Long JE, Xu D, Rubenstein JL 1996 Sequence, organization, and transcription of the Dlx-1 and Dlx-2 locus. Genomics (35):473-85
Links:	MGI:1339104 same experiment
	Ensembl same gene
	Allen Brain Atlas same gene
	BioGPS same gene
	International Mouse Knockout Project Status same gene
	GEISHA Chicken ISH Database same gene
	EMBL-EBI Gene Expression Atlas same gene
	BrainStars same gene
	ViBrism same gene
Data Source