EMAGE mouse gene expression spatial database

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EMAGE:3634

Dlx1 distal-less homeobox 1 ( MGI:94901)
TS15 (9.5 dpc)
in situ hybridisation

Data Images


Fig6A Copyright: Reprinted with permission from Elsevier from [doi:10.1006/dbio.1997.8556] Dev Biol 185: 165-84, Qiu M; Bulfone A; Ghattas I; Meneses JJ; Christensen L; Sharpe PT; Presley R; Pedersen RA; Rubenstein JL, Role of the Dlx homeobox genes in proximodistal patterning of the branchial arches: mutations of Dlx-1, Dlx-2, and Dlx-1 and -2 alter morphogenesis of proximal skeletal and soft tissue structures derived from the first and second arches. Copyright 1997	Fig6B Copyright: Reprinted with permission from Elsevier from [doi:10.1006/dbio.1997.8556] Dev Biol 185: 165-84, Qiu M; Bulfone A; Ghattas I; Meneses JJ; Christensen L; Sharpe PT; Presley R; Pedersen RA; Rubenstein JL, Role of the Dlx homeobox genes in proximodistal patterning of the branchial arches: mutations of Dlx-1, Dlx-2, and Dlx-1 and -2 alter morphogenesis of proximal skeletal and soft tissue structures derived from the first and second arches. Copyright 1997

Expression pattern clarity:
Find spatially similar wholemount expression patterns:

Notes:

Image annotations: Figure A shows a lateral view of the entire embryo; figure B shows a frontal view of dissected first and second arches. L- limb; H - hyoid (second) branchial arch; Md - mandibular branch of first branchial arch; Mx - maxillary branch of first branchial arch; O - otic vesicle.

Expression Pattern Description

Spatial Annotation:

Annotation colour key:

	strong
	moderate
	weak
	possible
	not detected

wholemount mapping

Download individual expression domains:

3634_wholemount_strong_3D_1.wlz

3634_wholemount_moderate_3D_1.wlz

3634_wholemount_weak_3D_1.wlz

3634_wholemount_possible_3D_1.wlz

3634_wholemount_notDetected_3D_1.wlz

(what is wlz format?)

Download all expression domains:

EMAGE:3634_all_domains.zip

Find spatially similar wholemount expression patterns:

EMAGE spatially similar wholemount patterns

Morphological match to the template:

Text Annotation:

Structure

Level

Pattern

Notes

1st branchial arch

detected

regional

Dlx-1 is expressed in the mesenchyme along much or all of the proximodistal axis of the first and second arches.

2nd branchial arch

detected

regional

Dlx-1 is expressed in the mesenchyme along much or all of the proximodistal axis of the first and second arches.

1st branchial arch maxillary component

detected

Annotation Validation:

EMAGE Editor

Detection Reagent

Type:	in situ hybridisation probe
Identifier:	MGI:32409
Entity Detected:	Dlx1, distal-less homeobox 1 ( MGI:94901)
Sequence:	sense strand is shown >MGI:32409 CAGGCGTTGGGGGCGGGCGAAGGGTGGGGACAGCAAGGGGGAGGGCGACGGCAGGGCGCGGCTGGTTGGT TTCTGGGGCGGGAAGCGCGCGAGGGAGGCGGGAGGCTGGAGTCGCGCGCCTTCGAGGTTCCTGCGCGGAC GCCGCAGCCCATTGTGCGTCCCGCTCCGCGCGCTCTGTTGCAGAGGAGCCCCGGCCGGGACGTGTGGACC GGATTCTCCCCAGGCCGGGCCGCGTCGCCCGCTCTAGTCCAGCCGAGCCCGAGCTTCTCGGACCAATCCC CGGTGATTATGCAAGAGAGCCGACCAATCAGCTCCACCAGCTCATGAATATTTATGACCTTGGCTGAGTC AAAGCTTTGAACCGAGTTTGGGGAGCTCGGCAGCATCATGCTTAGACTTTTCAAAGAGACAAACTCCATT TTCTTATGAATGGAAAGTGAAAACCCCTGTTCCGCTTAAATTGGGTTCCTTCCTGTCCTGAGAAACATAG AGACCCCCAAAAGGGAAGCAGAGGAGAGAAAGACCCACACCCAGACCCCGCGAGAAGAGATGACCATGAC CACCATGCCAGAAAGTCTCAACAGCCCCGTGTCGGGCAAGGCTGTGTTTATGGAGTTTGGGCCGCCCAAC CAGCAAATGTCTCCTTCTCCCATGTCCCACGGGCACTACTCCATGCACTGTTTACACTCGGCGGGCCATT CGCAGCCCGACGGTGCCTACAGTTCGGCCTCATCCTTCTCCCGACCGCTGGGCTACCCCTACGTCAACTC GGTCAGCAGCCACGCGTCCAGCCCCTACATCAGTTCCGTGCAGTCCTACCCCGGCAGCGCCAGCCTCGCC CAGAGCCGCCTGGAGGACCCAGGGGCGGACTCCGAGAAGAGTACGGTGGTGGAAGGCGGCGAGGTGCGCT TTAACGGCAAAGGGAAAAAGATCCGTAAACCCAGGACAATTTATTCCAGTTTGCAGTTGCAGGCTTTGAA CCGGAGGTTCCAACAAACTCAGTACTTAGCTCTGCCTGAGAGGGCGGAGCTGGCGGCCTCCTTGGGACTC ACACAGACGCAGGTCAAGATATGGTTCCAGAACAAACGCTCCAAGTTCAAGAAGCTGATGAAGCAAGGCG GGGCAGCTCTGGAGGGCAGCGCGCTGGCGAACGGCAGAGCCTTGTCTGCCGGCTCCCCACCGGTACCACC CGGCTGGAATCCGAACTCCTCATCTGGGAAGGGCTCCGGCAGCAGCGCTGGCTCCTACGTCCCCAGCTAT ACATCATGGTATCCCTCAGCGCACCAAGAAGCTATGCAGCAGCCTCAACTGATGTGAGGTTATCAGTTCG CACTCACCCGCTTCCTGCCCGTCTCCCTTGGCCCGGCCCCTCCCGCCTCCAGGTTCATCCACCTTTTCGC ACGCCCTGGGCCAGGAGGAGAAGAGCCCACGAGCGGGAGCAGGGGTGGGGGTGGGGAGCTAAAAATAAAA GAAAAAGGAACAGTGAAGGCAGAGGGCTTGCTGCTTCTCGGAGCCCCTAAAAGTCTGACTCAGCGACCTT TCAGCCCGAATCTGGTTTGGGCCACGGTGAACAGCAGAGTGGCCTCAAAGCGCAGGCACAGCCACTGGAG ACAGCCAGTGCCACAAGATAACCCGCTGGACCGGACCAGACTCTCATCTTTGTGAGACTATCAGGAAAAA CAAATACGTAGGAGGGGGAAATACGCTCTTTTTTGATTCTGTCCGTCTTTGTCTCCTTTTTGCACTGTCT GTGCGCCGAAGTCAAGGTCCTCGTGTGTCTGCTGTCCTCATTCTACGACCTCTCCAAAAAGTCACCAGGT CTGAGCCACACCGGTCTGCCGGCAGCCCATCCACCGAGTCCTGGACCACTTTTTCCTGAATGGTCTTCTT CCGGGCCCTGCTTGACCATCTATGTAGCTTGTTTGGGAAATGGGGGAAATCAGAGGGAGGGGGGTTAATT TATTGAAAAACAGACTTCATCTGACGCTGAGTGTTGGCCAATTCCAAATTCTCTGGGACATGGAGTGGGC GCTGTCCAAACATACTATTTACCTTAAACACACCAGAAGAGGGAACAAGGACAGGAAAGTGACTTTTAAG GTGCACAGTAACTTTTGTACTTGGCTGAAATGCAGAAAGGGAAAACAGGATGCCGTGCATTTTACATGCT CCAAATTATTAAAAATAACAACAAAAGAAAGACCGAAGTAAGGAAGTAAGATATGTAAAACCAATAGGAT GTTGTCAAAAACGTTTGGACAAGAACACCTGGCCAAGAAGAAAAATCATACTTTGGGCAGCAAGAGAGAG GACCAATGAGCCTTGGAGAGAAAATAATTTGTCCTTTATGTAAAAGCACCCCAATTCCAGGTCGCTTTAA AGTAAGACACAAGCAGCGGCTCGACCACAGAACACAAGTCATCACCCTGAATGCACGGGCTCTGGTGCAA GATCTAATTGCTGTACATATTATTGTTGTTATTATTATTAATTATTATTATTATTGTTCTGTAAACATGT TGCACAAGCTTAGCCTCTTTCCGTTCTGTTGTGTGTGGCTGTAAACCCGATGCTTTGTGAAATGAGAATC TTGACATTTTACTTGTGAAATTTGGAAAATGTGACCGATTGAAATCCACCGTGTTTTGTGTTCTCTATGT CAAAGTTTAGTTTTATATTGAGAATGTTAACTTATTGCTTTGTATCTTGGGGGGGGGGCGAACTTTGTAA ATAAGTTATAAAGTTTCTTTGAGACAGTAAAATTATGGTTTCAAGAAAG
	nt 1 - nt 2779 of U51001.1
Notes:	The Dlx1 probe used in this study by Qiu et al., 1997 [PMID:9187081] was described as "generated from a full-length (2.8-kb) Dlx-1 cDNA clone (McGuinness et al., 1996 [PMID:8812481] ." Editors Note: U51001.1 is the sequence submitted to GenBank to accompany the McGuinness et al., 1996 publication.
Chemistry:	RNA
Strand:	antisense

Specimen

Organism:	mouse
Age:	9.5 dpc
Theiler Stage:	TS15
Mutations:	none (wild-type)
Preparation:	wholemount

Procedures

General Information

Authors:	Qiu M; Bulfone A; Ghattas I; Meneses JJ; Christensen L; Sharpe PT; Presley R; Pedersen RA; Rubenstein JL, 1997 [PMID:9187081] , Indexed by GXD, Spatially Mapped by EMAGE.
Submitted by:	EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:	non-screen
References:	[ doi:10.1006/dbio.1997.8556] [ PMID:9187081] Qiu M, Bulfone A, Ghattas I, Meneses JJ, Christensen L, Sharpe PT, Presley R, Pedersen RA, Rubenstein JL 1997 Role of the Dlx homeobox genes in proximodistal patterning of the branchial arches: mutations of Dlx-1, Dlx-2, and Dlx-1 and -2 alter morphogenesis of proximal skeletal and soft tissue structures derived from the first and second arches. Dev Biol (185):165-84
	[ doi:10.1006/geno.1996.0387] [ PMID:8812481] McGuinness T, Porteus MH, Smiga S, Bulfone A, Kingsley C, Qiu M, Liu JK, Long JE, Xu D, Rubenstein JL 1996 Sequence, organization, and transcription of the Dlx-1 and Dlx-2 locus. Genomics (35):473-85
Links:	MGI:1339104 same experiment
	Ensembl same gene
	Allen Brain Atlas same gene
	BioGPS same gene
	International Mouse Knockout Project Status same gene
	GEISHA Chicken ISH Database same gene
	EMBL-EBI Gene Expression Atlas same gene
	BrainStars same gene
	ViBrism same gene
Data Source