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EMAGE:3635

Dlx2 distal-less homeobox 2 ( MGI:94902)
TS17 (10.5 dpc)
in situ hybridisation

Data Images
EMAGE:3635 EMAGE:3635
Fig 7CCopyright: Reprinted with permission from Elsevier from [doi:10.1006/dbio.1997.8556] Dev Biol 185: 165-84, Qiu M; Bulfone A; Ghattas I; Meneses JJ; Christensen L; Sharpe PT; Presley R; Pedersen RA; Rubenstein JL, Role of the Dlx homeobox genes in proximodistal patterning of the branchial arches: mutations of Dlx-1, Dlx-2, and Dlx-1 and -2 alter morphogenesis of proximal skeletal and soft tissue structures derived from the first and second arches. Copyright 1997 Fig 7DCopyright: Reprinted with permission from Elsevier from [ [doi:10.1006/dbio.1997.8556] Dev Biol 185: 165-84, Qiu M; Bulfone A; Ghattas I; Meneses JJ; Christensen L; Sharpe PT; Presley R; Pedersen RA; Rubenstein JL, Role of the Dlx homeobox genes in proximodistal patterning of the branchial arches: mutations of Dlx-1, Dlx-2, and Dlx-1 and -2 alter morphogenesis of proximal skeletal and soft tissue structures derived from the first and second arches. Copyright 1997

Expression pattern clarity: three stars
Find spatially similar expression patterns: Find spatially similar patterns
Notes:
Image annotations: Arrows point to expression of Dlx-2 in the surface ectoderm of the first arch; M - presumed mesoderm of mandibular arch. Both sections depict Dlx2 expression, however only the data from Fig7C was spatially annotated in this EMAGE entry.
Expression Pattern Description
Spatial Annotation:
EMAGE:3635EMAGE:3635Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
3D mappingspatial mapping

View mapped 3D expression image EMAGE genex expression entry
Download individual expression domains:
3635_voxel_strong_3D_1.wlz
3635_voxel_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:3635_all_domains.zip
Find spatially similar expression patterns: EMAGE spatially similar patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
1st branchial arch
detected detected
regionalDlx-2 is expressed in both proximal and distal regions of the first and second arches. The Dlx genes also have a graded expression along the mediolateral axis of the arches, with much lower levels of Dlx-2 in the extreme medial mesenchyme.
2nd branchial arch
detected detected
regionalDlx-2 is expressed in both proximal and distal regions of the first and second arches. The Dlx genes also have a graded expression along the mediolateral axis of the arches, with much lower levels of Dlx-2 in the extreme medial mesenchyme.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:1339090
Entity Detected:Dlx2, distal-less homeobox 2 ( MGI:94902)
Notes:The Dlx2 probe used in this study by Qiu et al., 1997 [PMID:9187081] is of unreported sequence.
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Age:10.5 dpc
Theiler Stage:TS17
Mutations:none (wild-type)
Preparation:section
Procedures
Staining procedure:autoradiography
General Information
Authors:Qiu M; Bulfone A; Ghattas I; Meneses JJ; Christensen L; Sharpe PT; Presley R; Pedersen RA; Rubenstein JL, 1997 [PMID:9187081] , Indexed by GXD, Spatially Mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1006/dbio.1997.8556] [ PMID:9187081] Qiu M, Bulfone A, Ghattas I, Meneses JJ, Christensen L, Sharpe PT, Presley R, Pedersen RA, Rubenstein JL 1997 Role of the Dlx homeobox genes in proximodistal patterning of the branchial arches: mutations of Dlx-1, Dlx-2, and Dlx-1 and -2 alter morphogenesis of proximal skeletal and soft tissue structures derived from the first and second arches. Dev Biol (185):165-84
Links:MGI:1339100 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI