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EMAGE:3661

Foxa1 forkhead box A1 ( MGI:1347472)
TS14
in situ hybridisation

Data Images
EMAGE:3661 EMAGE:3661 EMAGE:3661
Figure 4G. Copyright: This image is from Sasaki H, Development 1993 May;118(1):47-59, and is displayed with the permission of The Company of Biologists Limited who owns the Copyright. Figure 4E. Copyright: This image is from Sasaki H, Development 1993 May;118(1):47-59, and is displayed with the permission of The Company of Biologists Limited who owns the Copyright. Figure 4F. Copyright: This image is from Sasaki H, Development 1993 May;118(1):47-59, and is displayed with the permission of The Company of Biologists Limited who owns the Copyright.

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Find spatially similar expression patterns: Find spatially similar patterns
Notes:
Note: E: Lateral view of E9 embryo. Staining in the heart is non-specific. F,G: Planes of section are indicated as f and g in E. ev, eye vesicle; fg, foregut; h, heart; hg, hindgut; l, liver primordium; mb, midbrain; nc, notochord. Scale bars: 100um F; 200um G; 250um E.
Expression Pattern Description
Spatial Annotation:
EMAGE:3661EMAGE:3661EMAGE:3661EMAGE:3661Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
3D mapping3D mappingspatial mappingwholemount mapping

View mapped 3D expression image EMAGE genex expression entry
Download individual expression domains:
3661_wholemount_strong_3D_3.wlz
3661_wholemount_moderate_3D_1.wlz
3661_wholemount_notDetected_3D_3.wlz
3661_voxel_notDetected_3D_1.wlz
3661_voxel_strong_3D_1.wlz
3661_voxel_possible_3D_1.wlz
3661_voxel_notDetected_3D_2.wlz
3661_voxel_strong_3D_2.wlz
(what is wlz format?)
Download all expression domains: EMAGE:3661_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Find spatially similar expression patterns: EMAGE spatially similar patterns
Morphological match to the template: one star
Text Annotation:
StructureLevelPatternNotes
future midbrain floor plate
strong strong
gut
strong strong
visceral organ system
strong strong
regionalExpression is detected in the liver primordium.
notochord
weak weak
regionalExpression is detected in the posterior notochord and posterior floor plate of the neural tube
neural tube floor plate
weak weak
regionalExpression is detected in the posterior notochord and posterior floor plate of the neural tube
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:19191
Entity Detected:Foxa1, forkhead box A1 ( MGI:1347472)
Notes:The Foxa1 (HNF-3a) probe used in this study by Sasaki & Hogan, 1993 [PMID:8375339] was transcribed from the entire 2.0kb insert of a clone called c24. Editors note: the region of the Foxa1 cDNA that clone c24 covers is not defined by the authors.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Strain:(ICR x Swiss Webster)F1
Theiler Stage:TS14
Mutations:none (wild-type)
Preparation:sectioned wholemount
Procedures
Fixation:4% paraformaldehyde
Embedding:paraffin
Staining procedure:alkaline phosphatase + NBT/BCIP
General Information
Authors:Sasaki H; Hogan BL, 1993 [PMID:8375339] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:8375339] Sasaki H, Hogan BL 1993 Differential expression of multiple fork head related genes during gastrulation and axial pattern formation in the mouse embryo. Development (118):47-59
Links:MGI:1339061 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI