Quicksearch Help

(Click the icon to keep this page displayed.)

EMAGE:3666

Foxa2 forkhead box A2 ( MGI:1347476)
TS14 (9.5 dpc)
immunohistochemistry

Data Images
EMAGE:3666 EMAGE:3666
Figure 7A. Copyright: This image is from Nishina et al., Development 126: 505-516 (1998), and is displayed with the permission of The Company of Biologists Limited who owns the Copyright. Figure 7C. Copyright: This image is from Nishina et al., Development 126: 505-516 (1998), and is displayed with the permission of The Company of Biologists Limited who owns the Copyright.

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Note: nt, notochord; hb, hepatic bud; C is enhanced image of A.
Expression Pattern Description
Spatial Annotation:
EMAGE:3666Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
3666_wholemount_strong_3D_1.wlz
3666_wholemount_moderate_3D_1.wlz
3666_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:3666_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
embryo
detected detected
regional
notochord
detected detected
regionalSee Fig 7C
biliary bud intrahepatic part
detected detected
regionalSee Fig 7C
Annotation Validation: EMAGE Editor
Detection Reagent
Type:antibody
Identifier:MGI:1278428
Entity Detected:Foxa2, forkhead box A2 ( MGI:1347476)
Notes:The anti-FOXA2(HNF3beta) antibody used in this study by Nishina et al., 1999 [PMID:9876179] is described as "a primary rabbit anti-HNF3b antiserum".
Antibody Type:polyclonal
Raised In:rabbit
Specimen
Organism:mouse
Strain:involves: 129P2/OlaHsd * C57BL/6
Age:9.5 dpc
Theiler Stage:TS14
Mutations:Map2k4tm1Pngr/Map2k4+
Preparation:wholemount
Procedures
Fixation:methanol/DMSO 4:1
Secondary Antibody:goat anti-rabbit
Labelled with:horse radish peroxidase
Visualisation method:DAB
General Information
Authors:Nishina H; Vaz C; Billia P; Nghiem M; Sasaki T; De la Pompa JL; Furlonger K; Paige C; Hui C; Fischer KD; Kishimoto H; Iwatsubo T; Katada T; Woodgett JR; Penninger JM, 1999 [PMID:9876179] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:9876179] Nishina H, Vaz C, Billia P, Nghiem M, Sasaki T, De la Pompa JL, Furlonger K, Paige C, Hui C, Fischer KD, Kishimoto H, Iwatsubo T, Katada T, Woodgett JR, Penninger JM 1999 Defective liver formation and liver cell apoptosis in mice lacking the stress signaling kinase SEK1/MKK4. Development (126):505-16
Links:MGI:1327864 same experiment
 MGI:1857536 allele description
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI