EMAGE mouse gene expression spatial database

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EMAGE:3677

Foxc2 forkhead box C2 ( MGI:1347481)
TS17 (10.5 dpc)
in situ hybridisation

Data Images


Figure 10E. Copyright: This image is from Iida et al., Development 124: 4627-4638 (1997), and is displayed with the permission of The Company of Biologists Limited who owns the Copyright.	Figure 10F. Copyright: This image is from Iida et al., Development 124: 4627-4638 (1997), and is displayed with the permission of The Company of Biologists Limited who owns the Copyright.	Figure 10G. Copyright: This image is from Iida et al., Development 124: 4627-4638 (1997), and is displayed with the permission of The Company of Biologists Limited who owns the Copyright.	Figure 10H. Copyright: This image is from Iida et al., Development 124: 4627-4638 (1997), and is displayed with the permission of The Company of Biologists Limited who owns the Copyright.	Figure 10I. Copyright: This image is from Iida et al., Development 124: 4627-4638 (1997), and is displayed with the permission of The Company of Biologists Limited who owns the Copyright.

Figure 10J. Copyright: This image is from Iida et al., Development 124: 4627-4638 (1997), and is displayed with the permission of The Company of Biologists Limited who owns the Copyright.

Expression pattern clarity:
Find spatially similar expression patterns:

Notes:

Note: E,F are transverse sections through the optic cup. In G,H Rathke's pouch (bold arrow), trigeminal ganglion (V), medial nasal process (large asterisk) and lateral nasal mass (small asterisk) are indicated. Scale bar, 100 microns.

Expression Pattern Description

Spatial Annotation:

Annotation colour key:

	strong
	moderate
	weak
	possible
	not detected

3D mapping

spatial mapping

View mapped 3D expression image

Download individual expression domains:

3677_voxel_moderate_3D_1.wlz

3677_voxel_notDetected_3D_1.wlz

3677_voxel_strong_3D_1.wlz

3677_voxel_moderate_3D_2.wlz

3677_voxel_weak_3D_1.wlz

3677_voxel_notDetected_3D_2.wlz

3677_voxel_moderate_3D_3.wlz

3677_voxel_possible_3D_1.wlz

3677_voxel_notDetected_3D_3.wlz

3677_voxel_strong_3D_2.wlz

(what is wlz format?)

Download all expression domains:

EMAGE:3677_all_domains.zip

Find spatially similar expression patterns:

Morphological match to the template:

Text Annotation:

Structure

Level

Pattern

Notes

head mesenchyme

strong

eye mesenchyme

strong

body-wall mesenchyme

not detected

homogeneous

mesenchyme

detected

Expression was detected in mesenchymal cells between the hindbrain and foregut endoderm.

rathke's pouch

detected

1st branchial arch maxillary component

not detected

homogeneous

nasal process

not detected

homogeneous

1st branchial arch mandibular component

detected

inner ear

detected

Expression was detected around the vesticular portion of the otic vesicle.

1st branchial arch

detected

regional

Expression was weak in the perichordal region and absent in the medial region of the first branchial arch.

Annotation Validation:

EMAGE Editor

Detection Reagent

Type:	in situ hybridisation probe
Identifier:	MGI:1339605
Entity Detected:	Foxc2, forkhead box C2 ( MGI:1347481)
Sequence:	sense strand is shown >MGI:1339605 CGGCCGCGCGCGCCGGCCTGGTGGTGCCACCGCTGGCACTGCCATACGCCGCAGCGCCACCCGCCGCTTA CACGCAGCCGTGCGCGCAGGGCCTGGAGGCTGCGGGCTCCGCGGGCTACCAGTGCAGTATGCGGGCTATG AGTCTGTACACCGGGGCCGAGCGGCCCGCGCACGTGTGCGTTCCGCCCGCGCTGGACGAGGCTCTGTCGG ACCACCCGAGCGGCCCCGGCTCCCCGCTCGGCGCCCTCAACCTCGCAGCGGGTCAGGAGGGCGCGTTGGG GGCCTCGGGTCACCACCACCAGCATCACGGCCACCTCCACCCGCAGGCGCCACCGCCCGCCCCGCAGCCC CCTCCCGCGCCGCAGCCCGCCACCCAGGCCACCTCCTGGTATCTGAACCACGGCGGGGACCTGAGCCACC TCCCCGGCCACACGTTTGCAACCCAACAGCAAACTTTCCCCAACGTCCGGGAGATGTTCAACTCGCACCG GCTAGGACTGGACAACTCGTCCCTCGGGGAGTCCCAGGTGAGCAATGCGAGCTGTCAGCTGCCCTATCGA GCTACGCCGTCCCTCTACCGCCACGCAGCCCCCTACTCTTACGACTGCACCAAATACTGAGGCTGTCCAG TCCGCTCCAGCCCCAGGACCGCACCGGCTTCGCCTCCTCCATGGGAACCTTCTTCGACGGAGCCGCAGAA AGCGACGGAAAGCGCCCCTCTCTCAGAACCAGGAGCAGAGAGCTCCGTGCAACTCGCAGGTAACTTATCC GCAGCTCAGTTTGAGATCTCAGCGAGTCCCTCTAAGGGGGATGCAGCCCAGCAAAACGAAATACAGATTT TTTTTTTAATTCCTTCCCCTACCCAGATGCTGCGCCTGCTCCCTTGGGGCTTCATAGATTAGCTTATGGA CCAAACCCATAGGGACCCCTAATGACTTCTGTGGAGATTCTCCACGGGCGCAAGAGGTCTCTCCGGATAA GGTGCCTTCTGTAAACGAGTGCGGATTTGTAACCAGGCTATTTTGTTCTTGCCCAGAGCCTTTAATATAA TATTTAAAGTTGTGTCCACTGGATAAGGTTTCGTCTTGCCCAACTGTTACTGCCAAATTG
	nt 828 - nt 1937 of S63607.1
Notes:	The Foxc2 probe used in this study by Iida et al., 1997 [PMID:9409679] was described as the "NotI-EcoRI fragment of the MFH1 [Foxc2] cDNA (Miura et al, 1993 [PMID:8325367] (S63607.1))".
Chemistry:	RNA
Strand:	antisense

Specimen

Organism:	mouse
Age:	10.5 dpc
Theiler Stage:	TS17
Mutations:	none (wild-type)
Preparation:	section

Procedures

Fixation:	4% paraformaldehyde
Embedding:	paraffin

General Information

Authors:	Iida K; Koseki H; Kakinuma H; Kato N; Mizutani-Koseki Y; Ohuchi H; Yoshioka H; Noji S; Kawamura K; Kataoka Y; Ueno F; Taniguchi M; Yoshida N; Sugiyama T; Miura N, 1997 [PMID:9409679] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:	EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:	non-screen
References:	[ PMID:9409679] Iida K, Koseki H, Kakinuma H, Kato N, Mizutani-Koseki Y, Ohuchi H, Yoshioka H, Noji S, Kawamura K, Kataoka Y, Ueno F, Taniguchi M, Yoshida N, Sugiyama T, Miura N 1997 Essential roles of the winged helix transcription factor MFH-1 in aortic arch patterning and skeletogenesis. Development (124):4627-38
	[ doi:10.1016/0014-5793(93)81785-X] [ PMID:8325367] Miura N, Wanaka A, Tohyama M, Tanaka K 1993 MFH-1, a new member of the fork head domain family, is expressed in developing mesenchyme. FEBS Lett (326):171-6
Links:	MGI:1339703 same experiment
	Ensembl same gene
	Allen Brain Atlas same gene
	BioGPS same gene
	International Mouse Knockout Project Status same gene
	GEISHA Chicken ISH Database same gene
	EMBL-EBI Gene Expression Atlas same gene
	BrainStars same gene
	ViBrism same gene
Data Source