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EMAGE:3715

Cited1 Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 ( MGI:108023)
TS11 (EHF Downs & Davies)
in situ hybridisation

Data Images
EMAGE:3715 EMAGE:3715
Figure 3C. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/S0925-4773(98)00011-2] Mech Dev 72: 27-40, Dunwoodie SL; Rodriguez TA; Beddington RS, Msg1 and Mrg1, founding members of a gene family, show distinct patterns of gene expression during mouse embryogenesis. Copyright 1998. Figure 3D. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/S0925-4773(98)00011-2] Mech Dev 72: 27-40, Dunwoodie SL; Rodriguez TA; Beddington RS, Msg1 and Mrg1, founding members of a gene family, show distinct patterns of gene expression during mouse embryogenesis. Copyright 1998.

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Find spatially similar expression patterns: Find spatially similar patterns
Notes:
Note: C, lateral view, posterior to right. Early head-fold stage embryo, the visceral endoderm (arrowhead), mesoderm adjacent to the primitive streak (arrow). D, a proximal transverse section of the embryo in (C), mesodermal component of the primitive streak (arrow), the visceral endoderm (VE) (arrowhead). Scale bar: 135 microns.
Expression Pattern Description
Spatial Annotation:
EMAGE:3715EMAGE:3715EMAGE:3715Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
3D mappingspatial mappingwholemount mapping

View mapped 3D expression image EMAGE genex expression entry
Download individual expression domains:
3715_wholemount_strong_3D_2.wlz
3715_wholemount_moderate_3D_2.wlz
3715_wholemount_weak_3D_1.wlz
3715_wholemount_notDetected_3D_2.wlz
3715_voxel_strong_3D_1.wlz
3715_voxel_moderate_3D_1.wlz
3715_voxel_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:3715_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Find spatially similar expression patterns: EMAGE spatially similar patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
visceral extraembryonic endoderm
detected detected
embryo mesoderm
detected detected
regionalExpression is in the mesoderm adjacent to the primitive streak and is absent in the more mature mesoderm underlying the neural folds.
primitive streak
detected detected
regionalExpression is in the mesodermal component.
yolk sac endoderm
detected detected
Expression in visceral yolk sac endoderm
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:1309759
Entity Detected:Cited1, Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 ( MGI:108023)
Sequence:sense strand is shown

>MGI:1309759
AGTGCGCTGCCGAGCTGCGGTGAGGAAGCTAGCTCCGCCCGGCTGCTCCTCCCACAACCTATCGGCGCGG
GGCTGCTCCTGGCAGAGAGGACCAGACGCGAGGAAGGCACAGCACCCACTCGGGCCCTCCACCAACAGGC
CCAGCTGGCGGCATCAACTGCCACCGATTTATCGGACTTCTGCCCAGGCTCTGAAATGCCAACTATGTCG
AGGCCTGCACTTGATGTCAAGGGTGGCACCACCTCTGGGAAGGAGGATGCCAACCAGGAGATGAACTCTC
TGGCCTACTCCAACCTTGGAGTGAAGGATCGCAAGGCAGTGACTGTCCTGCACTACCCCGGGGTCACCGC
AAATGGAGCCAAAGCCAACGGAGTTCCCACTAGCTCCTCTGGATCGACATCTCCAATAGGCTCTCCTACT
GCCACCCCTTCTTCCAAACCCCCATCCTTCAACCTGCATCCTACCCCTCACCTGATGGCCAGCATGCAGC
TTCAGAAGCTTAATAGCCAGTACCAAGGGGCTGCGGCTACTGCTGCTGCTGCCCTCACTGGTGCAGGCCT
ACCAGGGGAGGAAGAGCCCATGCAAAACTGGGTCACCGCCCCTCTGGTAGTGGGAGGGTCTCCGGGATCT
GTCTCTCCTCCTGCTGGTGCCCAGAGCCCTGCTCTCATTGATTCTGACCCGGTGGATGAGGAGGTGCTGA
TGTCTCTGGTGGTTGAATTGGGGCTAGACCGAGCCAATGAGCTTCCCGAGCTGTGGCTGGGGCAGAATGA
GTTTGATTTCACTGCAGATTTTCCCTCTGGCTGCTGATGGCAAGTGCCCCTAAAAAAATGCGGAAAAAAA
GCCACCGATTCTGTTGTAAATAAAAGTTAACTTGCAAAGAGAT
nt 1 - nt 883 of U65091.1
Notes:The Cited1 (Msg1) probe used in this study by Dunwoodie, 1998 [PMID:9533950] was "the full-length Msg1 cDNA". The authors also state that "the Msg1 cDNA consists of 882 nucleotides and contains an open reading frame (ORF) of 203 amino acids as described by Shioda et al. (1996) [PMID:8901575] ". Editors note: U65091 is the accompanying GenBank entry for the cDNA clone described by Shioda et al.
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Strain:involves: C57BL/6 * DBA
Age:EHF Downs & Davies
Theiler Stage:TS11
Mutations:none (wild-type)
Preparation:sectioned wholemount
Procedures
Fixation:4% paraformaldehyde
Embedding:paraffin
General Information
Authors:Dunwoodie SL; Rodriguez TA; Beddington RS, 1998 [PMID:9533950] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1016/S0925-4773(98)00011-2] [ PMID:9533950] Dunwoodie SL, Rodriguez TA, Beddington RS 1998 Msg1 and Mrg1, founding members of a gene family, show distinct patterns of gene expression during mouse embryogenesis. Mech Dev (72):27-40
 [ doi:10.1073/pnas.93.22.12298] [ PMID:8901575] Shioda T, Fenner MH, Isselbacher KJ 1996 msg1, a novel melanocyte-specific gene, encodes a nuclear protein and is associated with pigmentation. Proc Natl Acad Sci U S A (93):12298-303
Links:MGI:3046752 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI