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EMAGE:3753

Dll3 delta-like 3 (Drosophila) ( MGI:1096877)
TS15 (9.5 dpc)
in situ hybridisation

Data Images
EMAGE:3753 EMAGE:3753 EMAGE:3753 EMAGE:3753
Figure 2B. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/S0925-4773(00)00514-1] Mech Dev 100: 141-4, Kusumi K; Dunwoodie SL; Krumlauf R, Dynamic expression patterns of the pudgy/spondylocostal dysostosis gene Dll3 in the developing nervous system. Copyright 2001. Figure 2A. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/S0925-4773(00)00514-1] Mech Dev 100: 141-4, Kusumi K; Dunwoodie SL; Krumlauf R, Dynamic expression patterns of the pudgy/spondylocostal dysostosis gene Dll3 in the developing nervous system. Copyright 2001. Figure 2C. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/S0925-4773(00)00514-1] Mech Dev 100: 141-4, Kusumi K; Dunwoodie SL; Krumlauf R, Dynamic expression patterns of the pudgy/spondylocostal dysostosis gene Dll3 in the developing nervous system. Copyright 2001. Figure 2D. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/S0925-4773(00)00514-1] Mech Dev 100: 141-4, Kusumi K; Dunwoodie SL; Krumlauf R, Dynamic expression patterns of the pudgy/spondylocostal dysostosis gene Dll3 in the developing nervous system. Copyright 2001.

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Figs A and B are views of an intact, whole-mount stained embryo. Figs C and D show views of a dissected neural tube at the same stage of development. Image annotations: V - fifth (or trigeminal) ganglion; r - rhombomere; mb - midbrain; hb - hindbrain; sc - spinal cord.
Expression Pattern Description
Spatial Annotation:
EMAGE:3753Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
3753_wholemount_strong_3D_1.wlz
3753_wholemount_moderate_3D_1.wlz
3753_wholemount_possible_3D_1.wlz
3753_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:3753_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
trigeminal v preganglion
detected detected
see Figs 2A and 2B.
neural tube lateral wall
detected detected
see Figs 2C and 2D.
future midbrain
detected detected
see Fig 2D.
rhombomere 02
strong strong
see Figs 2C and 2D.
rhombomere 04
strong strong
see Figs 2C and 2D.
rhombomere 05
not detected not detected
homogeneoussee Figs 2C and 2D.
rhombomere 06
not detected not detected
homogeneoussee Figs 2C and 2D.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:2446515
Entity Detected:Dll3, delta-like 3 (Drosophila) ( MGI:1096877)
Notes:The Dll3 probe used in this study by Kusumi et al., 2001 [PMID:11118901] was originally described in Dunwoodie et al., 1997 [PMID:9272948] and was derived from either "[clone] PS93 (1075-2243 bp) or [clone] Delta-S (1-2102 bp)". See Figure 1 therein or GenBank Y11895. It is unclear which was used in this experiment.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:9.5 dpc
Theiler Stage:TS15
Mutations:none (wild-type)
Preparation:wholemount
Procedures
Staining procedure:alkaline phosphatase + NBT/BCIP
General Information
Authors:Kusumi K; Dunwoodie SL; Krumlauf R, 2001 [PMID:11118901] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1016/S0925-4773(00)00514-1] [ PMID:11118901] Kusumi K, Dunwoodie SL, Krumlauf R 2001 Dynamic expression patterns of the pudgy/spondylocostal dysostosis gene Dll3 in the developing nervous system. Mech Dev (100):141-4
 [ PMID:9272948] Dunwoodie SL, Henrique D, Harrison SM, Beddington RS 1997 Mouse Dll3: a novel divergent Delta gene which may complement the function of other Delta homologues during early pattern formation in the mouse embryo. Development (124):3065-76
Links:MGI:3611832 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI