EMAGE mouse gene expression spatial database

Quicksearch Help

(Click the icon to keep this page displayed.)

EMAGE:3758

Jag2 jagged 2 ( MGI:1098270)
TS15 (9 dpc)
in situ hybridisation

Data Images


Figure 1A. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/S0925-4773(97)00146-9] Mech Dev 69: 203-7, Valsecchi C; Ghezzi C; Ballabio A; Rugarli EI, JAGGED2: a putative Notch ligand expressed in the apical ectodermal ridge and in sites of epithelial-mesenchymal interactions Copyright 1997.

Expression pattern clarity:
Find spatially similar wholemount expression patterns:

Notes:

Note: I, first branchial arch; II, second branchial arch. The arrowhead points to expression in the apical ectodermal ridge.

Expression Pattern Description

Spatial Annotation:

Annotation colour key:

	strong
	moderate
	weak
	possible
	not detected

wholemount mapping

Download individual expression domains:

3758_wholemount_strong_3D_1.wlz

3758_wholemount_moderate_3D_1.wlz

3758_wholemount_possible_3D_1.wlz

3758_wholemount_notDetected_3D_1.wlz

(what is wlz format?)

Download all expression domains:

EMAGE:3758_all_domains.zip

Find spatially similar wholemount expression patterns:

EMAGE spatially similar wholemount patterns

Morphological match to the template:

Text Annotation:

Structure

Level

Pattern

Notes

forelimb bud ectoderm

detected

regional

Expression is in the apical ectodermal ridge.

1st branchial arch

detected

regional

Expression in ectoderm.

Annotation Validation:

EMAGE Editor

Detection Reagent

Type:	in situ hybridisation probe
Identifier:	MGI:2429866
Entity Detected:	Jag2, jagged 2 ( MGI:1098270)
Sequence:	sense strand is shown >MGI:2429866 CAATGCTGAGCCTGACCAATACCTCTGCGCCTGCCCAGATGGCTACTTGGGCAAGAACTGTGAGCGGGCT GAGCACGCCTGTGCCTCCAACCCGTGTGCCAATGGGGGCTCTTGCCACGAAGTGCCATCTGGCTTTGAAT GCCACTGTCCGTCAGGATGGAGCGGACCCACCTGTGCGCTCGACATTGATGAGTGTGCCTCTAACCCATG TGCAGCGGGTGGTACCTGCGTGGATCAGGTGGACGGCTTCGAGTGCATCTGCCCGGAGCAGTGGGTGGGG GCTACTTGCCAGCTGGACGCCAATGAGTGTGAAGGGAAGCCGTGCCTTAATGCTTTTTCTTGCAAAAACC TGATTGGCGGCTATTACTGTGATTGCCTCCCGGGCTGGAAGGGCATCAACTGCCAAATCAACATCAACGA TTGTCATGGGCAGTGTCAGCATGGGGGCACCTGCAAGGACCTGGTCAATGGGTACCAGTGTGTGTGCCCG CGGGGCTTTGGAGGTCGCCATTGCGAACTAGAGTACGACAAGTGTGCCAGCAGCCCCTGCCGCCGGGGTG GCATCTGCGAGGACCTGGTGGATGGCTTCCGCTGCCACTGCCCACGGGGCCTCTCTGGGCTGCACTGTGA GGTGGACATGGATCTCTGTGAACCAAGCCCCTGCCTCAACGGTGCTCGCTGCTACAACCTTGAGGGTGAC TACTACTGCGCCTGCCCAGAAGACTTTGGTGGCAAGAACTGCTCAGTGCCCAGGGACACATGCCCTGGCG GGGCATGTAGAGTGATCGATGGCTGCGGGTTCGAGGCAGGGTCCAGGGCACGCGGTGTCGCACCCTCTGG TATATGTGGCCCTCACGGGCACTGCGTTAGCCTGCCTGGGGGAAACTTCTCCTGCATCTGTGACAGCGGC TTCACAGGCACCTACTGCCATGAAAACATTGACGACTGCATGGGCCAGCCCTGCCGCAACGGGGGCACGT GCATTGACGAAGTGGACTCCTTCCGCTGCTTCTGCCCCAGTGGCTGGGAAGGAGAACTCTGTGACATCAA TCCCAACGACTGCCTCCCCGACCCCTGCCACAGCCGCGGCCGCTGCTATGACCTGGTCAATGACTTCTAC TGTGCCTGTGACGATGGCTGGAAGGGCAAGACCTGCCACTCACGCGAGTTCCAGTGTGACGCCTACACCT GCAGCAACGGTGGCACATGCTATGACAGCGGCGACACCTTTCCTGCGCGTCCTCCGGGCTGGAAGGGCAG CACCTGCACCATCGCCAAGAACAGCAGCTGTGTGCCCAATCCC
	nt 1 - nt 1303 of Y14495.1
Notes:	The Jag2 probe used in this study by Valsecchi et al., 1997 [PMID:9486542] is described as such: "Clone S2 (GenBank Y14495) was used as template for the digoxygenin-labelled RNA probe".
Chemistry:	RNA
Strand:	antisense
Label:	digoxigenin

Specimen

Organism:	mouse
Age:	9 dpc
Theiler Stage:	TS15
Mutations:	none (wild-type)
Preparation:	wholemount

Procedures

Fixation:

4% paraformaldehyde

General Information

Authors:	Valsecchi C; Ghezzi C; Ballabio A; Rugarli EI, 1997 [PMID:9486542] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:	EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:	non-screen
References:	[ doi:10.1016/S0925-4773(97)00146-9] [ PMID:9486542] Valsecchi C, Ghezzi C, Ballabio A, Rugarli EI 1997 JAGGED2: a putative Notch ligand expressed in the apical ectodermal ridge and in sites of epithelial-mesenchymal interactions. Mech Dev (69):203-7
Links:	MGI:2429962 same experiment
	Ensembl same gene
	Allen Brain Atlas same gene
	BioGPS same gene
	International Mouse Knockout Project Status same gene
	GEISHA Chicken ISH Database same gene
	EMBL-EBI Gene Expression Atlas same gene
	BrainStars same gene
	ViBrism same gene
Data Source