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EMAGE:3890

Pmel premelanosome protein ( MGI:98301)
TS17 (10.5 dpc)
in situ hybridisation

Data Images
EMAGE:3890
Figure 2C. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/j.modgep.2003.07.002] Gene Expr Patterns 3: 703-7, Baxter LL; Pavan WJ, Pmel17 expression is Mitf-dependent and reveals cranial melanoblast migration during murine development. Copyright 2003.

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Note: Arrowhead indicates cells extending from the midbrain-hindbrain boundary, arrow points to cells extending towards the eye.
Expression Pattern Description
Spatial Annotation:
EMAGE:3890Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
3890_wholemount_strong_3D_1.wlz
3890_wholemount_moderate_3D_1.wlz
3890_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:3890_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
surface ectoderm
strong strong
regionalExpression is in melanoblasts at the dorsal surface of the midbrain-hindbrain boundary and in cells extending from this region laterally and towards the developing eye.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:3028550
Entity Detected:Pmel, premelanosome protein ( MGI:98301)
Notes:The Si (gp100/gp87/Pmel17) probe used in this study by Baxter & Pavan, 2003 [PMID:14643677] is indicated as being generated from RIKEN clone G3B70039D15T3, which was provided by Piero Carninci and Yoshihide Hayashizaki. Editors Note: No sequence for this clone could be found by searching NCBI or RIKEN databases.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Strain:FVB/NJ
Age:10.5 dpc
Theiler Stage:TS17
Mutations:none (wild-type)
Preparation:wholemount
Procedures
Staining procedure:alkaline phosphatase + BMpurple
General Information
Authors:Baxter LL & Pavan WJ, 2003 [PMID:14643677] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1016/j.modgep.2003.07.002] [ PMID:14643677] Baxter LL, Pavan WJ 2003 Pmel17 expression is Mitf-dependent and reveals cranial melanoblast migration during murine development. Gene Expr Patterns (3):703-7
Links:MGI:3028556 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI