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EMAGE:3914

Fgf3 fibroblast growth factor 3 ( MGI:95517)
TS17 (10.25 dpc)
in situ hybridisation

Data Images
EMAGE:3914
Fig 2C. Copyright: Reprinted with permission from Elsevier from [doi:10.1006/dbio.1996.0081] Dev Biol 174: 370-8, McKay IJ; Lewis J; Lumsden A, The role of FGF-3 in early inner ear development: an analysis in normal and kreisler mutant mice. Copyright 1996

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image annotations: white arrowhead - expression in the developing vestibuloacoustic ganglion.
Expression Pattern Description
Spatial Annotation:
EMAGE:3914Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
3914_wholemount_strong_3D_1.wlz
3914_wholemount_moderate_3D_1.wlz
3914_wholemount_possible_3D_1.wlz
3914_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:3914_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
otocyst
weak weak
regionalExpression is localized to the rostroventrolateral portion of the otocyst.
ear
weak weak
regionalThere is weak expression in the otic epithelium.
1st branchial pouch endoderm
detected detected
regionalFGF-3 is expressed in the endoderm lining the ends of the pharyngeal pouches.
2nd branchial pouch endoderm
detected detected
regionalFGF-3 is expressed in the endoderm lining the ends of the pharyngeal pouches.
3rd branchial pouch endoderm
detected detected
regionalFGF-3 is expressed in the endoderm lining the ends of the pharyngeal pouches.
acoustic viii ganglion
weak weak
Weak expression is detected in the vestibuloacoustic ganglion.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:1336138
Entity Detected:Fgf3, fibroblast growth factor 3 ( MGI:95517)
Notes:The Fgf3 Probe used in this study by McKay IJ et al., 1996 [PMID:8631508] is described as "a gift of D. Wilkinson (MRC, Mill Hill) consisting of 0.5kb of untranslated 3' mRNA." This probe recognises all the transcripts of Fgf3.
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Strain:(CBA x C3H/He)F1
Age:10.25 dpc
Theiler Stage:TS17
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:McKay IJ; Lewis J; Lumsden A, 1996 [PMID:8631508] , Indexed by GXD, Spatially Mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1006/dbio.1996.0081] [ PMID:8631508] McKay IJ, Lewis J, Lumsden A 1996 The role of FGF-3 in early inner ear development: an analysis in normal and kreisler mutant mice. Dev Biol (174):370-8
Links:MGI:1336140 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI