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EMAGE:3920

Gata2 GATA binding protein 2 ( MGI:95662)
TS18 (10.5 dpc)
in situ hybridisation

Data Images
EMAGE:3920 EMAGE:3920 EMAGE:3920 EMAGE:3920 EMAGE:3920
Fig3A. Copyright: Reprinted with permission from Elsevier from [doi:10.1006/dbio.1999.9278] Dev Biol 210: 305-21, Nardelli J; Thiesson D; Fujiwara Y; Tsai FY; Orkin SH, Expression and genetic interaction of transcription factors GATA-2 and GATA-3 during development of the mouse central nervous system. Copyright 1999 Fig3-cartoon. Copyright: Reprinted with permission from Elsevier from [doi:10.1006/dbio.1999.9278] Dev Biol 210: 305-21, Nardelli J; Thiesson D; Fujiwara Y; Tsai FY; Orkin SH, Expression and genetic interaction of transcription factors GATA-2 and GATA-3 during development of the mouse central nervous system. Copyright 1999 Fig3B. Copyright: Reprinted with permission from Elsevier from [doi:10.1006/dbio.1999.9278] Dev Biol 210: 305-21, Nardelli J; Thiesson D; Fujiwara Y; Tsai FY; Orkin SH, Expression and genetic interaction of transcription factors GATA-2 and GATA-3 during development of the mouse central nervous system. Copyright 1999 Fig3C. Copyright: Reprinted with permission from Elsevier from [doi:10.1006/dbio.1999.9278] Dev Biol 210: 305-21, Nardelli J; Thiesson D; Fujiwara Y; Tsai FY; Orkin SH, Expression and genetic interaction of transcription factors GATA-2 and GATA-3 during development of the mouse central nervous system. Copyright 1999 Fig3D. Copyright: Reprinted with permission from Elsevier from [doi:10.1006/dbio.1999.9278] Dev Biol 210: 305-21, Nardelli J; Thiesson D; Fujiwara Y; Tsai FY; Orkin SH, Expression and genetic interaction of transcription factors GATA-2 and GATA-3 during development of the mouse central nervous system. Copyright 1999
EMAGE:3920
Fig3E. Copyright: Reprinted with permission from Elsevier from [doi:10.1006/dbio.1999.9278] Dev Biol 210: 305-21, Nardelli J; Thiesson D; Fujiwara Y; Tsai FY; Orkin SH, Expression and genetic interaction of transcription factors GATA-2 and GATA-3 during development of the mouse central nervous system. Copyright 1999

Expression pattern clarity: three stars
Find spatially similar expression patterns: Find spatially similar patterns
Notes:
Approximate section planes of images 3A, B, C, D and E are shown in the cartoon.
Expression Pattern Description
Spatial Annotation:
EMAGE:3920EMAGE:3920EMAGE:3920EMAGE:3920EMAGE:3920Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
3D mapping3D mapping3D mapping3D mappingspatial mapping

View mapped 3D expression image EMAGE genex expression entry
Download individual expression domains:
3920_voxel_moderate_3D_1.wlz
3920_voxel_notDetected_3D_1.wlz
3920_voxel_strong_3D_1.wlz
3920_voxel_moderate_3D_2.wlz
3920_voxel_notDetected_3D_2.wlz
3920_voxel_strong_3D_2.wlz
3920_voxel_moderate_3D_3.wlz
3920_voxel_notDetected_3D_3.wlz
3920_voxel_strong_3D_3.wlz
3920_voxel_moderate_3D_4.wlz
3920_voxel_notDetected_3D_4.wlz
3920_voxel_strong_3D_4.wlz
(what is wlz format?)
Download all expression domains: EMAGE:3920_all_domains.zip
Find spatially similar expression patterns: EMAGE spatially similar patterns
Morphological match to the template: one star
Text Annotation:
StructureLevelPatternNotes
central nervous system ganglion
detected detected
regionalExpression is weaker in the ventricular than in the subventricular zone in the common oculomotor nucleus.
rhombomere 01
detected detected
regionalExpression is detected throughout the mediolateral axis of the ventral neural tube in r1, with a marked activation in a cluster of cells with juxtapose the floor plate.
rhombomere 04
detected detected
regionalExpression is detected in a ventral domain of r4, the most lateral of which extends to the floor plate.
rhombomere 06
detected detected
regionalExpression is observed in two distinct domains: one close to the floor plate and a more dorsal one, expanding laterally throughout the neural tube.
future spinal cord
detected detected
regionalExpression in the spinal cord is activated ventrally in both the ventricular and subventricular zone, but is excluded from the mantle layer.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:1339608
Entity Detected:Gata2, GATA binding protein 2 ( MGI:95662)
Notes:The Gata2 probe used in this study by Nardelli et al., 1999 [PMID:10357893] is described as "A 5' 700-bp portion of GATA-2 cDNA, not including the finger domains."
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:10.5 dpc
Theiler Stage:TS18
Mutations:none (wild-type)
Preparation:sectioned wholemount
Procedures
Embedding:cryosection
General Information
Authors:Nardelli J; Thiesson D; Fujiwara Y; Tsai FY; Orkin SH, 1999 [PMID:10357893] , Indexed by GXD, Spatially Mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1006/dbio.1999.9278] [ PMID:10357893] Nardelli J, Thiesson D, Fujiwara Y, Tsai FY, Orkin SH 1999 Expression and genetic interaction of transcription factors GATA-2 and GATA-3 during development of the mouse central nervous system. Dev Biol (210):305-21
Links:MGI:1342722 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI